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What to Do During Severe Hypoglycemia: A Life-Saving Action Plan

05 Sep 2025 M. Regina Castro, M.D.

What to Do During Severe Hypoglycemia: A Life-Saving Action Plan

Severe hypoglycemia, or low blood sugar, is a critical and potentially life-threatening condition that primarily affects individuals with diabetes, especially those who use insulin or certain oral medications to manage their blood sugar levels. Understanding how to recognize and respond to severe hypoglycemia is essential for both the individual at risk and their family, friends, and caregivers. This article provides a comprehensive action plan, covering everything from identifying the symptoms to taking immediate and effective steps to address the situation.

Hypoglycemia, in general, occurs when the glucose level in the blood drops too low, typically below 70 mg/dL (3.9 mmol/L). When blood sugar falls to such a degree that the person becomes mentally or physically incapacitated and requires assistance from another individual, it’s considered severe.

The goal of this guide is to empower you with the knowledge and strategies needed to respond effectively during such an emergency, potentially saving a life.


Recognizing the Signs and Symptoms of Severe Hypoglycemia

The first step in managing severe hypoglycemia is recognizing its symptoms. While mild to moderate hypoglycemia can manifest with symptoms like shakiness, sweating, dizziness, and hunger, severe hypoglycemia presents a more alarming array of signs. It's important to remember that these symptoms can vary among individuals, and some might experience them differently.

Common Signs and Symptoms of Severe Hypoglycemia:

  • Loss of Consciousness: The individual may faint or become unresponsive.
  • Seizures: Uncontrolled muscle spasms can occur as the brain is deprived of glucose.
  • Confusion and Disorientation: Marked difficulty in thinking clearly, speaking coherently, or knowing where they are.
  • Inability to Swallow or Cooperate: This prevents the safe oral administration of glucose.
  • Unusual Behavior: Erratic actions that are out of character for the individual.
  • Combativeness or Agitation: Especially in states of confusion, the individual may become irritable or aggressive.

It is crucial not to assume that an unconscious or confused person is simply intoxicated or experiencing some other condition. Always consider hypoglycemia, especially if the person is known to have diabetes or is wearing a medical identification bracelet or necklace indicating they have the condition.

| Symptom | Description | Importance | | :------------------------- | :-------------------------------------------------------------------------------- | :------------------------------------------------------------------------------------------------------- | | Loss of Consciousness | Fainting or unresponsiveness; can quickly become dangerous if untreated. | Requires immediate intervention as the individual cannot help themselves. | | Seizures | Uncontrolled muscle spasms; can be frightening and potentially cause injury. | Needs careful monitoring and potentially emergency medical services to prevent further complications. | | Confusion/Disorientation | Inability to think clearly or understand surroundings. | Indicates a critical need for glucose as brain function is severely impaired. | | Inability to Cooperate | The person cannot swallow or follow simple instructions. | Prevents safe oral administration of treatment, necessitating alternative methods. | | Unusual Behavior | Acting erratically or in a manner uncharacteristic of their normal self. | Should prompt a high index of suspicion for hypoglycemia, especially in individuals with diabetes. | | Combativeness/Agitation | Becoming irritable or aggressive, often due to confusion and physical distress. | Requires caution and a calm approach to avoid escalation and ensure the person's safety. |

Understanding these signs enables quick recognition and action, which is key to preventing serious consequences.


The Immediate Action Plan: Step-by-Step Guide

When someone exhibits signs of severe hypoglycemia, time is of the essence. Here is a step-by-step guide on what to do:

Step 1: Check for Responsiveness and Safety

First, assess the situation:

  • Check for Responsiveness: Try to rouse the person by gently shaking them and speaking loudly. Ask them simple questions, such as "Are you okay?" or "What's your name?".
  • Ensure Safety: Make sure the area around the person is safe. Remove any potential hazards that could cause injury if they are having a seizure or are confused.

Step 2: Do NOT Give Anything by Mouth if Unconscious

It is crucial not to attempt to give food or liquids to someone who is unconscious, having a seizure, or unable to swallow. Doing so could lead to choking, aspiration pneumonia, or other serious complications. This rule also applies if the person is confused or uncooperative.

Step 3: Administer Glucagon (If Available and Trained)

Glucagon is a hormone that raises blood sugar levels by stimulating the liver to release stored glucose into the bloodstream. If a glucagon kit is available and you are trained to use it: How To Create A Diabetic Diet Plan To Lower Your Blood Sugar

  • Locate the Glucagon Kit: Ensure you know where glucagon kits are kept in the home, school, or workplace.
  • Prepare the Glucagon: Follow the instructions included in the glucagon kit precisely. Typically, this involves mixing a liquid with a powder in the syringe provided.
  • Administer the Glucagon: The injection is usually given into the thigh, buttock, or arm. Inject the glucagon as directed in the instructions.
  • Note the Time: Make a note of the time the glucagon was administered. This will be important for relaying information to emergency medical services.

Important Considerations for Glucagon Administration:

  • Training is Essential: Make sure that family members, caregivers, teachers, and coworkers know how to administer glucagon.
  • Keep Kits Up-to-Date: Check the expiration dates on glucagon kits regularly and replace them when necessary.
  • Side Effects: Common side effects of glucagon include nausea and vomiting. Be prepared to manage these after the person regains consciousness.

Step 4: Call Emergency Medical Services (EMS)

Whether or not glucagon is available or administered, always call EMS (911 in the United States) immediately if someone is experiencing severe hypoglycemia. Even if the person regains consciousness after glucagon, it is crucial to have them evaluated by medical professionals as soon as possible. There may be underlying reasons for the hypoglycemia, and further monitoring and treatment may be needed.

When calling EMS, provide the following information:

  • That the person is unconscious or having a seizure.
  • That you suspect severe hypoglycemia due to diabetes (if known).
  • Whether or not glucagon was administered and the time it was given.
  • The person's location, including any specific instructions for finding them (e.g., "behind the main building" or "apartment 3B").

Step 5: Monitoring and Aftercare

While waiting for EMS to arrive:

  • Monitor Breathing: Ensure the person is breathing. If not, be prepared to perform CPR if you are trained to do so.
  • Place in Recovery Position: If the person regains consciousness but is still weak or nauseous, place them on their side in the recovery position to prevent choking if they vomit.
  • Provide Oral Glucose (If Fully Conscious and Able to Swallow): Once fully awake and able to swallow, give the person fast-acting carbohydrates, such as glucose tablets, fruit juice, or regular (non-diet) soda. Follow this with a longer-acting source of carbohydrates like crackers or a sandwich.

Summary of Action Plan Steps:

| Step | Action | Rationale | | :------------------------ | :------------------------------------------------------------------------- | :--------------------------------------------------------------------------------------------------------------------------- | | 1. Check Responsiveness | Try to rouse the person by shaking and speaking. | To determine the level of consciousness and the severity of the situation. | | 2. Safety First | Ensure the area is safe and remove potential hazards. | To prevent injury during a seizure or period of confusion. | | 3. NO Oral Intake | Do NOT give food or liquid if unconscious, seizing, or unable to swallow. | To avoid choking or aspiration. | | 4. Administer Glucagon | Inject glucagon per kit instructions (if available and trained). | To raise blood glucose levels by stimulating the liver to release stored glucose. | | 5. Call EMS | Dial emergency services (911 in the U.S.). | To ensure the person receives prompt medical evaluation and treatment, especially if glucagon is ineffective or unavailable. | | 6. Monitor Breathing | Check for regular breathing; prepare for CPR if necessary. | To provide immediate life support if breathing stops. | | 7. Recovery Position | Place the conscious but weak person on their side. | To prevent choking in case of vomiting. | | 8. Oral Glucose | Give fast-acting carbohydrates once fully conscious and able to swallow. | To quickly raise blood glucose levels once it is safe to do so. |


Prevention Strategies to Minimize the Risk of Severe Hypoglycemia

While it's essential to know how to respond to severe hypoglycemia, preventing it in the first place is the best approach. Numerous strategies can help reduce the risk: Can You Lower Your A1C Without Medication A Look At Lifestyle Changes

  • Regular Blood Glucose Monitoring: Consistently checking blood sugar levels using a glucose meter or continuous glucose monitor (CGM) can help identify patterns and prevent lows. Individuals using insulin should check their blood sugar before meals, before bedtime, and before and after exercise.

  • Carbohydrate Counting: Learning to accurately count carbohydrates in meals and snacks is crucial for matching insulin doses to food intake.

  • Adjusting Insulin Doses: Work closely with a healthcare provider to adjust insulin doses based on food intake, activity levels, and blood glucose readings. Pay particular attention to adjusting doses for exercise, as physical activity can lower blood sugar levels.

  • Avoiding Skipping Meals: Regular meal times are essential to maintain stable blood sugar levels. Skipping meals, especially when taking insulin or other medications that lower blood sugar, can lead to hypoglycemia.

  • Limiting Alcohol Consumption: Alcohol can interfere with the liver's ability to release glucose and can increase the risk of hypoglycemia, especially when consumed without food. It is advisable to consume alcohol in moderation and always with a meal.

  • Being Aware of Medications: Certain medications, such as sulfonylureas, can increase the risk of hypoglycemia. Understanding how these medications work and monitoring blood glucose levels closely is important.

  • Wearing Medical Identification: A medical ID bracelet or necklace can alert others to the presence of diabetes in case of an emergency, ensuring that appropriate treatment is provided.

  • Educating Family and Friends: Make sure that family members, friends, and caregivers know the signs and symptoms of hypoglycemia and how to administer glucagon. Provide them with clear instructions and resources.

  • Using Technology: Utilize available technology, such as insulin pumps and continuous glucose monitors (CGMs). CGMs can alert individuals to impending lows, allowing them to take proactive measures to prevent severe hypoglycemia. Some CGMs can even communicate with insulin pumps to automatically adjust insulin delivery based on glucose levels.

| Prevention Strategy | Description | Benefit | | :------------------------------ | :--------------------------------------------------------------------------------------------- | :-------------------------------------------------------------------------------------------------- | | Regular Glucose Monitoring | Checking blood sugar frequently with a meter or CGM. | Allows for early detection of lows and proactive adjustments to prevent severe hypoglycemia. | | Carbohydrate Counting | Accurately measuring carbohydrates in meals and snacks. | Helps match insulin doses to food intake, preventing blood sugar swings. | | Insulin Dose Adjustment | Modifying insulin doses based on diet, activity, and glucose readings, under medical guidance. | Keeps blood sugar levels in target range and minimizes the risk of lows. | | Avoiding Skipped Meals | Eating meals at consistent times. | Prevents blood sugar from dropping too low, especially when taking medications. | | Limiting Alcohol | Consuming alcohol in moderation with food. | Reduces the risk of alcohol-induced hypoglycemia. | | Medication Awareness | Understanding how medications affect blood sugar. | Prevents medication-related hypoglycemia. | | Medical Identification | Wearing a medical ID bracelet or necklace. | Alerts others to diabetes in an emergency. | | Education of Loved Ones | Informing family and friends about hypoglycemia and how to treat it. | Ensures someone is prepared to help in an emergency. | | Utilizing Technology (CGM/Pump) | Using devices like continuous glucose monitors and insulin pumps. | Provides continuous monitoring and automated insulin delivery, reducing the risk of lows and highs. |


Legal and Ethical Considerations

When dealing with severe hypoglycemia, there are legal and ethical aspects to keep in mind:

  • Good Samaritan Laws: Many jurisdictions have Good Samaritan laws that protect individuals who provide assistance in an emergency. These laws are designed to encourage people to help others without fear of legal repercussions.

  • Consent: If the person is conscious and able to make decisions, obtain their consent before providing assistance, if possible. However, in an emergency situation where the person is unconscious or unable to give consent, it is generally accepted that implied consent exists, allowing you to provide necessary aid.

  • Standard of Care: When providing assistance, act in a reasonable and prudent manner, consistent with your training and knowledge. Avoid actions that could cause further harm to the individual.

  • Documentation: If possible, document the events that occurred, including the symptoms observed, interventions performed, and the time of these actions. This information can be helpful for medical professionals who subsequently treat the individual. Can You Lower High Blood Sugar Without Medication A Deep Dive

  • Confidentiality: Respect the person's privacy and confidentiality. Share information about their condition only with those who need to know, such as medical personnel.

  • Mandatory Reporting: In some cases, there may be a legal obligation to report certain incidents, such as suspected abuse or neglect. Be aware of any mandatory reporting requirements in your jurisdiction.

It is essential to act responsibly and ethically when responding to severe hypoglycemia. Your goal should always be to provide the best possible care while respecting the rights and dignity of the individual involved.


Conclusion: Be Prepared, Be Proactive, Save Lives

Severe hypoglycemia is a serious medical condition that requires immediate attention. Being prepared with the knowledge and resources to respond effectively can save lives. By understanding the signs and symptoms, following the action plan outlined in this article, and implementing preventative strategies, individuals with diabetes and their support networks can significantly reduce the risk and impact of severe hypoglycemia.

Remember to educate yourself, your family, and your community about this potentially life-threatening condition. Regular training, up-to-date glucagon kits, and a proactive approach to diabetes management are essential for ensuring the safety and well-being of those at risk. Staying vigilant, informed, and ready to act is the best way to handle the challenges posed by severe hypoglycemia and to ensure that those affected receive the help they need, when they need it most.

References and Further Reading