Severe Hypoglycemia: Recognizing the Emergency Signs and How to Help
05 Sep 2025 Gregory W. Barsness, M.D.
Severe Hypoglycemia: Recognizing the Emergency Signs and How to Help
Severe hypoglycemia, or low blood sugar, is a critical medical condition that can occur in people with diabetes, particularly those using insulin or certain oral medications. It's crucial to recognize the emergency signs of severe hypoglycemia and know how to respond effectively to prevent serious complications. This article will guide you through identifying the symptoms, understanding the immediate steps to take, and the importance of follow-up care.
Why Severe Hypoglycemia Is a Medical Emergency
Hypoglycemia occurs when the level of glucose (sugar) in the blood drops too low, usually below 70 mg/dL. While mild hypoglycemia might cause symptoms like shakiness or sweating, severe hypoglycemia is far more dangerous because the brain relies on glucose for energy. Without enough glucose, brain function is impaired, leading to potentially life-threatening situations. Recognizing the difference between mild and severe hypoglycemia is crucial for timely intervention.
Quick Summary: What You Need to Know About Severe Hypoglycemia
- Severe hypoglycemia is a critical medical emergency.
- It’s characterized by symptoms that indicate impaired brain function.
- Immediate action is necessary to raise blood sugar levels.
- Glucagon administration and emergency medical services are often required.
Identifying the Signs and Symptoms of Severe Hypoglycemia
Being able to identify the signs and symptoms of severe hypoglycemia is the first step in providing the right kind of help. These symptoms indicate that the brain is not receiving enough glucose, leading to impaired function. Here’s a detailed look at what to watch for:
Key Symptoms of Severe Hypoglycemia
- Loss of Consciousness:
- One of the most alarming signs is when the person becomes unresponsive or loses consciousness. This is a clear indication that brain function is severely compromised due to low blood sugar.
- Seizures:
- Seizures can occur as a result of the brain's electrical activity being disrupted by insufficient glucose. A person experiencing a seizure needs immediate medical attention.
- Confusion and Disorientation:
- Before losing consciousness, a person may show signs of significant confusion or disorientation. They might not recognize their surroundings, people they know, or understand simple questions.
- Inability to Swallow or Take Oral Medication:
- If someone is too confused or unable to cooperate, they may not be able to swallow food, drinks, or glucose tablets. This makes oral treatment impossible, necessitating alternative methods like glucagon.
- Unusual or Aggressive Behavior:
- Hypoglycemia can sometimes manifest as sudden changes in behavior, including aggression, irritability, or irrational actions. This is due to the effect of low blood sugar on brain function.
- Difficulty Speaking:
- Slurred speech or difficulty finding the right words can be another sign of severe hypoglycemia. The person might struggle to communicate clearly or make sense.
Distinguishing Between Mild and Severe Symptoms
It’s important to differentiate between mild and severe symptoms. Mild symptoms like sweating, shakiness, or hunger are warnings that blood sugar is dropping. However, when these progress to confusion, loss of consciousness, or seizures, it's a clear sign that severe hypoglycemia is occurring and needs immediate attention. How To Lower Blood Sugar Quickly 7 Tips For Immediate Relief
Real-World Example: Identifying a Severe Hypoglycemic Episode
Imagine you are at a family gathering, and your uncle, who has diabetes, suddenly becomes confused and starts slurring his words. He is unable to answer simple questions, and then he collapses. This scenario highlights the importance of recognizing severe hypoglycemia symptoms quickly.
| Symptom | Mild Hypoglycemia | Severe Hypoglycemia | | :---------------------- | :------------------------------------------ | :--------------------------------------------------- | | Shakiness | Present | May or may not be present | | Sweating | Present | May or may not be present | | Hunger | Present | May or may not be present | | Confusion | Mild, correctable with food/drink | Significant, unable to think clearly | | Loss of Consciousness | Absent | Present | | Seizures | Absent | Present | | Speech | Normal or slightly slurred | Significantly slurred, difficulty finding words | | Behavior | Normal or slightly irritable | Aggressive, irrational, or unusual |
How to Help Someone Experiencing Severe Hypoglycemia

When someone shows signs of severe hypoglycemia, quick action is essential to prevent serious complications. Here’s a step-by-step guide on how to respond effectively:
Step 1: Check for Responsiveness
First, try to rouse the person by speaking to them loudly or gently shaking their shoulder. If they do not respond or are only partially responsive, consider it a medical emergency.
Step 2: Do Not Give Food or Drink If Unconscious
Never attempt to give food or drink to someone who is unconscious, having a seizure, or unable to swallow. This can cause choking or aspiration, which can be fatal.
Step 3: Administer Glucagon (If Available and Trained)
- What is Glucagon? Glucagon is a hormone that raises blood sugar levels quickly. It comes in injectable and nasal spray forms and is prescribed for people at risk of severe hypoglycemia.
- How to Administer Glucagon Injection:
- Check the expiration date on the glucagon kit.
- Follow the instructions provided in the kit to prepare and administer the injection. Typically, you will inject glucagon into the thigh, arm, or buttock.
- After administering the glucagon, turn the person onto their side in the recovery position to prevent choking if they vomit.
- How to Administer Nasal Glucagon:
- Check the expiration date.
- Follow the instructions to insert the device into one nostril and press the plunger to deliver the dose.
Step 4: Call Emergency Medical Services (EMS)
Whether you have administered glucagon or not, immediately call your local emergency number (such as 911 in the US) or ask someone else to do so. Severe hypoglycemia requires professional medical attention.
- What to Tell the Emergency Operator:
- That the person is unresponsive and may be experiencing severe hypoglycemia.
- If they have diabetes.
- Whether glucagon was administered.
- Your location.
Step 5: Monitor the Person Until Help Arrives
Continuously monitor the person’s breathing and condition until EMS arrives. Be prepared to provide additional information to the paramedics about what happened.
Understanding the Role of Glucagon
Glucagon works by prompting the liver to release stored glucose into the bloodstream. It’s a critical tool for managing severe hypoglycemia outside of a hospital setting. However, glucagon is not a substitute for medical care, and it’s essential to seek professional help.
Real-World Example: Responding to a Severe Hypoglycemic Episode
John finds his roommate, who has diabetes, unconscious on the floor. He remembers his roommate mentioning a glucagon kit. John finds the kit, checks the expiration date, and follows the instructions to administer the glucagon injection into his roommate’s thigh. He then calls 911 and informs the operator about the situation, including the glucagon administration. John continues to monitor his roommate until the paramedics arrive. The Blood Sugar And Weight Loss Connection How To Master Your Glucose
| Step | Action | Why It’s Important | | :-------------------------------- | :---------------------------------------------------------------------------------- | :------------------------------------------------------------------------------------- | | Check Responsiveness | Try to wake the person | Determine the severity of the situation | | Do Not Give Food/Drink | Avoid giving anything orally | Prevent choking and aspiration | | Administer Glucagon (if trained) | Follow instructions to inject or administer glucagon nasally | Increase blood sugar levels quickly | | Call EMS | Inform emergency services and provide necessary details | Ensure professional medical help arrives | | Monitor the Person | Continuously check breathing and condition | Be ready to provide additional information to paramedics |
Important Considerations and Follow-Up Care
Following an episode of severe hypoglycemia, several important considerations and follow-up steps should be taken to prevent future occurrences and ensure the person's ongoing health.
1. Medical Evaluation and Adjustment of Treatment
After a severe hypoglycemic event, a thorough medical evaluation is necessary. The person's healthcare provider will review their diabetes management plan, including medication dosages, timing of insulin injections, meal plans, and blood glucose monitoring practices.
- Adjusting Medication: The healthcare provider might adjust the dosage or type of medication to reduce the risk of future hypoglycemia.
- Dietary Review: A registered dietitian can help review and modify the person's meal plan to ensure consistent carbohydrate intake.
- Exercise Plan: Adjustments to the exercise routine might be needed, along with advice on how to manage blood sugar levels during physical activity.
2. Diabetes Education and Training
Reinforcing diabetes education is essential. This includes teaching the person and their caregivers how to recognize the early signs of hypoglycemia, properly use a blood glucose meter, administer glucagon, and adjust insulin doses based on blood sugar readings.
- Hypoglycemia Awareness Training: Educate on recognizing subtle early symptoms to take action before it escalates.
- Glucagon Training: Ensure family members and close contacts know how to administer glucagon in an emergency.
- Continuous Glucose Monitoring (CGM): Consider using a CGM device that alerts the person and caregivers to low blood sugar trends.
3. Identifying the Cause of the Hypoglycemic Episode
Determining the cause of the severe hypoglycemia is crucial to prevent future occurrences. Common causes include:
- Missed or Delayed Meals: Ensure meals and snacks are taken on time.
- Excessive Insulin Dose: Review insulin dosages with a healthcare provider.
- Unplanned Exercise: Adjust insulin or carbohydrate intake before physical activity.
- Alcohol Consumption: Limit alcohol intake, as it can interfere with blood sugar regulation.
4. Psychological Support
Experiencing a severe hypoglycemic episode can be traumatic for both the person and their caregivers. Psychological support can help address any anxiety or fear associated with future episodes.
- Counseling: A therapist can provide coping strategies and reduce anxiety.
- Support Groups: Connecting with others who have experienced similar events can offer emotional support.
5. Developing an Emergency Plan
Creating a detailed emergency plan can help everyone respond quickly and effectively in case of another severe hypoglycemic episode. This plan should include:
- Contact Information: List of emergency contacts, including healthcare providers and family members.
- Glucagon Location: Clearly identify where the glucagon kit is stored and how to access it.
- Step-by-Step Instructions: Clear instructions on how to administer glucagon and when to call for emergency help.
- Medical Information: Information about the person’s diabetes, medications, and any other relevant medical conditions.
Table: Follow-Up Care Checklist After Severe Hypoglycemia
| Action Item | Description | Responsibility | | :------------------------------ | :------------------------------------------------------------------------------------------------- | :-------------------------------- | | Medical Evaluation | Review of diabetes management plan and medication adjustment | Healthcare Provider | | Diabetes Education | Training on recognizing symptoms, using glucagon, and managing blood sugar levels | Diabetes Educator | | Cause Identification | Identify factors that contributed to the hypoglycemic episode | Person with Diabetes, Caregiver | | Psychological Support | Counseling or support groups to address anxiety and fear | Mental Health Professional | | Emergency Plan Development | Create a detailed plan with contact information, glucagon location, and step-by-step instructions | Person with Diabetes, Caregiver | The Fasting Blood Glucose Test How To Prepare And Interpret Your Numbers
Real-World Example: Follow-Up Care
After experiencing a severe hypoglycemic episode, Sarah, who has type 1 diabetes, meets with her endocrinologist and a diabetes educator. They review her insulin dosages and adjust her meal plan to include more consistent carbohydrate intake. Her family members are trained on how to administer glucagon, and they develop an emergency plan that includes contact information and clear instructions. Sarah also joins a support group to help cope with her anxiety about future episodes.
Conclusion: Preparedness and Education Are Key
Severe hypoglycemia is a serious medical emergency that requires prompt recognition and immediate action. Understanding the signs and symptoms, knowing how to administer glucagon, and seeking professional medical help are crucial steps in managing this condition. Moreover, comprehensive follow-up care, including medical evaluations, diabetes education, and psychological support, is essential to prevent future episodes and improve the overall well-being of individuals with diabetes. Preparedness and education are the cornerstones of effective hypoglycemia management.
References and Further Reading
- a1c chart explained understanding your a1c levels and eag y2arnr
- the blood sugar diet plan what to eat to stabilize your glucose n1n8xz
- impaired fasting glucose the subtle warning sign you need to know pbUjUB
- the ultimate blood sugar diet what to eat for optimal glucose control nV5CMO
- what is a normal blood sugar level ranges for non diabetics explained tzNRqO