Feeling Shaky? It Could Be Severe Hypoglycemia (Low Blood Sugar)
05 Sep 2025 John F. Sullivan, D.O.
Feeling Shaky? It Could Be Severe Hypoglycemia (Low Blood Sugar)
Experiencing shakiness, sweating, or confusion can be alarming, especially if it happens suddenly. While these symptoms can stem from various causes, one potential culprit is severe hypoglycemia, more commonly known as low blood sugar. Hypoglycemia occurs when the level of glucose (sugar) in your blood drops below the normal range, depriving your brain and body of the energy they need to function properly. Understanding the symptoms, causes, and treatment of severe hypoglycemia is crucial, especially for individuals with diabetes or those at risk of developing it. This article will explore what severe hypoglycemia is, why it happens, how to recognize it, and, most importantly, what steps you can take to manage and prevent it.
What is Hypoglycemia and Why Is It a Problem?
Hypoglycemia is defined as a blood glucose level below 70 mg/dL (3.9 mmol/L). Glucose is the primary source of energy for your body's cells, including those in the brain. When blood sugar levels drop too low, the brain doesn't receive enough fuel, leading to a range of symptoms. Mild hypoglycemia can often be managed with a quick snack or a sugary drink, but severe hypoglycemia requires more immediate and often external intervention.
Severe hypoglycemia is a critical condition where low blood sugar levels impair cognitive function to the point that the individual needs assistance from another person to recover. This might involve administering glucagon or providing assistance to consume sugar-containing foods or drinks. Ignoring severe hypoglycemia can lead to serious consequences, including seizures, loss of consciousness, coma, and, in rare cases, even death. Fasting Blood Glucose Understanding Your Numbers And Your Risk
Here's a quick breakdown:
| Level of Hypoglycemia | Blood Glucose Level (mg/dL) | Symptoms | Required Action | |-----------------------|------------------------------|------------------------------------------------------|--------------------------------------------------------------------------------------------------------------------| | Mild | 70-55 | Shakiness, sweating, hunger, irritability | Consume 15-20 grams of fast-acting carbohydrates (e.g., juice, hard candy, glucose tablets) and recheck in 15 mins | | Moderate | 55-40 | Confusion, difficulty concentrating, weakness | Consume 15-20 grams of fast-acting carbohydrates. If no improvement, seek medical help. | | Severe | Below 40 | Loss of consciousness, seizures, inability to function | Requires immediate assistance. Administer glucagon if available and call emergency services. |
Recognizing the Signs and Symptoms of Severe Hypoglycemia
Being able to identify the symptoms of hypoglycemia, especially the severe form, is crucial for prompt intervention. The symptoms can vary from person to person and can also depend on how quickly the blood sugar level drops.
Common Symptoms of Hypoglycemia (Progressing to Severe):
- Shakiness: Uncontrollable trembling or shaking.
- Sweating: Sudden and excessive perspiration, often clammy.
- Dizziness or Lightheadedness: Feeling unsteady or faint.
- Confusion: Difficulty thinking clearly or making decisions.
- Irritability or Anxiety: Feeling unusually agitated or nervous.
- Rapid Heartbeat: A noticeably fast pulse.
- Hunger: An intense craving for food.
- Blurred Vision: Difficulty seeing clearly.
- Weakness: General feeling of being tired and lacking energy.
- Headache: Persistent or throbbing pain in the head.
- Loss of Coordination: Difficulty with movement and balance.
Symptoms that Indicate Severe Hypoglycemia (Requiring Immediate Assistance):
- Disorientation: Not knowing where you are or what is happening.
- Difficulty Speaking: Slurred speech or inability to communicate clearly.
- Seizures: Uncontrolled muscle spasms or convulsions.
- Loss of Consciousness: Passing out or becoming unresponsive.
It’s important to note that some people may not experience the typical warning signs of hypoglycemia, a condition known as hypoglycemia unawareness. This can be particularly dangerous, as individuals may not realize their blood sugar is low until it reaches a severely low level. People with long-standing diabetes or frequent episodes of hypoglycemia are more prone to developing hypoglycemia unawareness.
Understanding the Causes and Risk Factors of Severe Hypoglycemia
While hypoglycemia can affect anyone, it's most commonly associated with diabetes. Several factors can contribute to severe hypoglycemia, particularly in individuals managing diabetes with insulin or certain oral medications. How To Manage Blood Sugar Spikes After Meals With These Diet Tips
Common Causes and Risk Factors:
- Excessive Insulin Dosage: Taking too much insulin, either intentionally or accidentally, is a leading cause of hypoglycemia. This can happen if the wrong dose is administered, or if there is a mismatch between insulin dosage and carbohydrate intake.
- Skipping or Delaying Meals: Missing meals or snacks, or delaying them for too long, can lead to a drop in blood sugar levels.
- Inadequate Carbohydrate Intake: Not consuming enough carbohydrates to match insulin dosage, particularly during meals, can result in hypoglycemia.
- Increased Physical Activity: Strenuous exercise can increase insulin sensitivity and glucose utilization, potentially leading to low blood sugar levels, especially if carbohydrate intake isn’t adjusted accordingly.
- Alcohol Consumption: Alcohol can interfere with the liver's ability to release glucose into the bloodstream, increasing the risk of hypoglycemia, especially when consumed without food.
- Certain Medications: Some oral diabetes medications, such as sulfonylureas (e.g., glipizide, glyburide), can stimulate the pancreas to release more insulin, increasing the risk of hypoglycemia. Other medications, such as some antibiotics or anti-malarial drugs, can also contribute to low blood sugar.
- Kidney or Liver Disease: Impaired kidney or liver function can affect insulin metabolism and glucose regulation, increasing the risk of hypoglycemia.
- Hormonal Deficiencies: Conditions affecting the adrenal glands or pituitary gland can lead to hormonal imbalances that increase the risk of hypoglycemia.
- Gastroparesis: This condition, often seen in people with diabetes, slows down the emptying of the stomach, making it difficult to predict how quickly food will be absorbed and can lead to unpredictable blood sugar fluctuations, including hypoglycemia.
- Accidental or Intentional Overdose of Oral Hypoglycemic Agents: Oral drugs can interact with other drugs, which can either elevate or decrease serum glucose levels.

Other Less Common Causes:
- Insulinoma: A rare tumor in the pancreas that produces excessive insulin.
- Reactive Hypoglycemia: Low blood sugar that occurs after eating, usually within a few hours after a meal. This can be caused by excessive insulin release in response to carbohydrate intake.
- Non-Diabetic Hypoglycemia: Hypoglycemia that occurs in people without diabetes. This can be caused by various factors, including certain medical conditions, medications, or dietary habits.
Risk factors also include age (both very young and very old individuals are more vulnerable), cognitive impairment, and a history of frequent hypoglycemic episodes.
Diagnosing Hypoglycemia: The Importance of Blood Glucose Monitoring
Diagnosing hypoglycemia involves measuring blood glucose levels, ideally at the time symptoms are present.
Methods for Diagnosing Hypoglycemia:
- Blood Glucose Meter: A portable device that measures blood glucose levels from a small sample of blood, typically obtained from a finger prick. This is the most common method for self-monitoring.
- Continuous Glucose Monitor (CGM): A device that continuously tracks blood glucose levels throughout the day and night, providing real-time information and alerts about highs and lows.
- Laboratory Blood Tests: Blood glucose levels can also be measured in a laboratory setting, which may be necessary for confirming a diagnosis or investigating the underlying cause of hypoglycemia.
The “Whipple’s triad” is a classic criterion used to diagnose hypoglycemia. It includes the following:
- Symptoms of hypoglycemia: Such as shakiness, sweating, confusion, etc.
- Low blood glucose level: Measured at the time symptoms occur.
- Relief of symptoms: When blood glucose levels are restored to normal.
If you suspect you have experienced severe hypoglycemia, it's essential to consult with a healthcare professional for proper diagnosis and management. They may recommend further testing to identify the underlying cause and develop an appropriate treatment plan. This might include a thorough review of your medications, diet, and lifestyle factors, as well as tests to assess kidney, liver, or hormonal function.
Treating Severe Hypoglycemia: A Step-by-Step Guide
Severe hypoglycemia is a medical emergency requiring immediate intervention. The primary goal of treatment is to raise blood glucose levels as quickly as possible.
Steps to Treat Severe Hypoglycemia:
-
Administer Glucagon (If Available):
- Glucagon is a hormone that stimulates the liver to release stored glucose into the bloodstream. It is available as an injectable medication or a nasal spray.
- If the person is unconscious or unable to swallow, glucagon should be administered immediately.
- Follow the instructions provided with the glucagon kit or nasal spray. Typically, the injection is given into the thigh, arm, or buttocks. The nasal spray is administered into one nostril.
- After administering glucagon, call emergency services (911 in the US) and monitor the person closely.
-
Call Emergency Services:
- Even if glucagon is administered, it’s crucial to call emergency services for further evaluation and treatment.
- Provide details about the person’s condition, including their medical history, medications, and any other relevant information.
-
Provide Fast-Acting Carbohydrates (If Conscious and Able to Swallow):
- If the person is conscious and able to swallow, give them fast-acting carbohydrates, such as:
- Glucose tablets or gel
- Fruit juice (4 ounces)
- Regular (non-diet) soda (4 ounces)
- Hard candies (e.g., lollipops)
- Honey or syrup (1 tablespoon)
- Avoid giving food or drinks that contain fat, such as chocolate or peanut butter, as these can slow down the absorption of glucose.
- If the person is conscious and able to swallow, give them fast-acting carbohydrates, such as:
-
Monitor Blood Glucose Levels:
- After administering glucagon or providing fast-acting carbohydrates, monitor the person's blood glucose levels every 15 minutes until they are above 70 mg/dL (3.9 mmol/L).
- If blood glucose levels do not improve or symptoms persist, repeat the treatment.
-
Provide a Sustained Source of Carbohydrates:
- Once blood glucose levels have returned to normal, provide a longer-acting source of carbohydrates, such as:
- A sandwich with protein
- Crackers with cheese
- A piece of fruit
- This will help to prevent a recurrence of hypoglycemia.
- Once blood glucose levels have returned to normal, provide a longer-acting source of carbohydrates, such as:
Important Considerations:
- Educate Family and Friends: Ensure that family members, friends, and caregivers know how to recognize and treat severe hypoglycemia, including how to administer glucagon.
- Wear a Medical Alert: Consider wearing a medical ID bracelet or necklace indicating that you have diabetes and are at risk of hypoglycemia.
- Carry a Hypoglycemia Kit: Always carry a kit containing fast-acting carbohydrates, glucagon (if prescribed), and a blood glucose meter.
Example Scenario:
Imagine you are at a restaurant with a friend who has type 1 diabetes. Suddenly, your friend becomes disoriented, confused, and starts sweating profusely. You notice that they are having difficulty speaking and appear to be losing consciousness.
- Recognize the symptoms: You identify that your friend is experiencing severe hypoglycemia based on the disorientation, confusion, sweating, and difficulty speaking.
- Administer Glucagon: You know your friend has a glucagon kit in their bag. You quickly retrieve it and administer the injection into their thigh, following the instructions provided.
- Call Emergency Services: While waiting for the glucagon to take effect, you immediately call 911 and provide the dispatcher with details about your friend’s condition and medical history.
- Monitor and Support: You stay with your friend, monitoring their breathing and pulse until emergency medical services arrive. You inform the paramedics about the glucagon administration and any other relevant information.
In this scenario, your quick thinking and knowledge of hypoglycemia treatment can potentially save your friend’s life.
Preventing Hypoglycemia: Long-Term Management Strategies
While treating severe hypoglycemia is critical, preventing it from occurring in the first place is even more important. Long-term management strategies are essential for minimizing the risk of hypoglycemia, particularly for individuals with diabetes.
Key Prevention Strategies:
-
Regular Blood Glucose Monitoring:
- Check blood glucose levels frequently, especially before meals, before and after exercise, and at bedtime.
- Use a continuous glucose monitor (CGM) for real-time tracking and alerts about potential lows.
-
Meal Planning and Timing:
- Eat regular meals and snacks, and avoid skipping or delaying them.
- Ensure that meals contain an adequate balance of carbohydrates, protein, and fat.
- Work with a registered dietitian or certified diabetes educator to develop a personalized meal plan.
-
Medication Management:
- Take diabetes medications as prescribed by your healthcare provider.
- Be aware of the potential side effects of medications, including hypoglycemia.
- Work closely with your healthcare provider to adjust medication dosages as needed, based on blood glucose levels, activity levels, and other factors.
-
Exercise Planning:
- Check blood glucose levels before, during, and after exercise.
- Adjust carbohydrate intake or insulin dosage as needed to prevent hypoglycemia during and after exercise.
- Carry a source of fast-acting carbohydrates during exercise.
-
Alcohol Consumption:
- Consume alcohol in moderation, and always with food.
- Check blood glucose levels before and after drinking alcohol.
- Be aware that alcohol can impair judgment and may mask the symptoms of hypoglycemia.
-
Education and Awareness:
- Educate yourself and your family about hypoglycemia, including its symptoms, causes, treatment, and prevention strategies.
- Attend diabetes education classes or support groups to learn from experts and connect with others who have diabetes.
-
Hypoglycemia Unawareness Management:
- If you experience hypoglycemia unawareness, work closely with your healthcare provider to develop a strategy to improve your ability to detect low blood sugar levels. This may involve temporarily raising your target blood glucose range or using a CGM with alerts.
Specific Tips for Preventing Hypoglycemia:
- Keep a Log: Track your blood glucose levels, food intake, medication dosages, and physical activity to identify patterns and potential triggers for hypoglycemia.
- Set Alarms: Set alarms on your phone to remind you to check your blood glucose levels, take medications, or eat snacks.
- Prepare for Travel: When traveling, pack extra medication, snacks, and supplies for treating hypoglycemia. Be aware of time zone changes and adjust medication schedules accordingly.
- Communicate with Your Healthcare Team: Maintain regular communication with your healthcare provider, diabetes educator, and other members of your healthcare team to address any concerns or challenges you may be facing.
By adopting these prevention strategies and working closely with your healthcare team, you can significantly reduce your risk of severe hypoglycemia and improve your overall health and well-being.
When to Seek Medical Attention and Long-Term Outlook
While many instances of hypoglycemia can be managed at home, it's essential to know when to seek professional medical help.
Seek Immediate Medical Attention If:
- You experience severe hypoglycemia, especially if you lose consciousness or have a seizure.
- You are unable to raise your blood glucose levels despite treatment.
- You have recurrent episodes of hypoglycemia, even with adjustments to your medication or diet.
- You develop symptoms of hypoglycemia unawareness.
- You experience any other concerning symptoms, such as chest pain, shortness of breath, or severe abdominal pain.
Long-Term Outlook:
With proper management and lifestyle modifications, most people with diabetes can effectively control their blood glucose levels and minimize their risk of hypoglycemia. However, it’s crucial to remain vigilant and proactive in managing your condition.
- Regular Check-ups: Attend regular check-ups with your healthcare provider to monitor your overall health and adjust your treatment plan as needed.
- Continuous Learning: Stay informed about the latest advancements in diabetes care and management by attending conferences, reading reputable sources, and engaging with online communities.
- Support System: Build a strong support system of family, friends, and healthcare professionals to help you navigate the challenges of living with diabetes and prevent complications such as hypoglycemia.
Ultimately, understanding the signs and symptoms of severe hypoglycemia, knowing how to treat it, and implementing effective prevention strategies are key to living a healthy and fulfilling life with diabetes. If you’re feeling shaky or experiencing any of the symptoms described in this article, take it seriously, check your blood sugar, and take appropriate action. Your well-being depends on it. Can You Lower Your A1C Through Diet A Look At The Evidence
References and Further Reading
- the ultimate blood sugar diet 10 meal ideas to stabilize your levels pluxIQ
- what is a normal blood sugar range a guide for adults before amp after eating NERSYF
- decoding your a1c blood sugar test a simple guide to the numbers vd02Q1
- normal blood sugar after eating what your post meal reading really means RV6m4T
- decoding your lab results understanding the a1c blood sugar test 3TZF2a