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Dr. Smita Jain

Dr. Smita Jain

Assistant Professor , Life Science

smita.jain@sharda.ac.in

About

Dr Smita Jain has more than 11 years of UG/PG teaching experience and had been associated with Department of Life Science, Sharda school of Biosciences and Technology from past 4 years. Prior to this employment, she worked as Assistant Professor (Ad-hoc) in the Department of Biochemistry, Institute of Home Economics, University of Delhi and was an active member in organizing Training cum hands-on workshop on Molecular biology and Immunobiology techniques at IHE. She has completed her MSc (Biotechnology), UGC-CSIR JRF-SRF scholar and PhD in Biochemistry from Delhi University. Her research domain includes the exploration of the neurodegenerative changes, cross talk between neurotransmitters and inflammatory pathways attributed to altered protein expression in various clinical disorders such as Migraine, Parkinsonism. She is also doing active research in identifying the potential benefits of metallic nanoparticles using green synthesis in amelioration of heavy metal induced toxicity. During her PhD tenure, she has identified the adverse toxicity of xenobiotics including pesticides and plant derived drugs with respect to its bioaccumulation and transport across the highly specific and impermeable blood-brain barrier, subsequent impact on the brain inhabited memory related proteins. She has published her research work in various peer reviewed national and international journals of high impact factor. She has also published few book chapters published nationally. She has co-authored a textbook on Medicinal Chemistry for undergraduate students. She has been awarded with an Institutional Research Grant by Research and Development Centre, Sharda University to explore the role of Vitamin D and memory neurotrophins in association with ferritin levels in migraine patients of North India. She has been monitoring the mapping of all academic work on university portal as Department ERP (Enterprise Resource Planning) champion from past two years.

Experience
  • 7 year research, 8 year Teaching
Qualification
  • B.Sc. Zoology (Hansraj College, DU)
  • M.Sc. Biotechnology (IAMR, CCSU)
  • Ph.D. Medical Biochemistry (Faculty of Medical Sciences, DU)
Award & Recognition

  • UGC CSIR JRF 2007
  • ICMR JRF 2007
  • UGC CSIR SRF 2011
  • Granted seed fund intramural grant from dean research Committee, Sharda University 2022
  • External examiner at various colleges for UG and PG Examination

Research

Total 10 research papers (8 International; 2 National)

Total 5 book chapters

Authored textbook (1)

 

  • Kumari S, Singh M, Nupur, Jain S, Verma N, Malik S, Rustagi S, Priya K. A review on therapeutic mechanism of medicinal plants against osteoporosis: effects of phytoconstituents. Mol Biol Rep. 2023 Nov;50(11):9453-9468. doi: 10.1007/s11033-023-08751-4. Epub 2023 Sep 7. PMID: 37676432.
  • Rana P, Sharma A, Jain S, Deshmukh P, Banerjee BD, Bhattacharya SK, Kumari P. Comparison of Fluoxetine and 1-Methyl-L-Tryptophan in treatment of depression like illness in Bacillus Calmette-Guerin induced inflammatory model of depression in mice. Journal of Basic and Clinical Physiology and Pharmacology 2016; 27(6):569-576.
  • Jain S, Banerjee BD, Ahmed RS, Arora VK, Mediratta PK. Possible role of Brain derived neurotrophic factor and oxidative stress in Triazophos induced cognitive impairment in rats. Neurochemical Research 2013; 38(9): 2136-47.
  • Sharma T, Jain S, Verma A, Sharma N, Gupta S, Arora VK, Banerjee BD. Gene- Environment interaction in urinary bladder cancer with special reference to organochlorine pesticides: A case control study.Cancer Biomarkers 2013; 13:243-251.
  • Bharathi SP, Raj HM, Jain S, Banerjee BD, Ahmed T, Arora VK. Role of pesticides in the induction of tumor angiogenesis. Anticancer Research 2013;33(1):231-240.
  • Saxena A, Nasre N, Jain S, Dhakte G, Ahmed R, Bhattacharya S, Mediratta P, Banerjee BD. A randomized, prospective study of efficacy and safety of oral Tramadol in the management of Post Herpetic Neuralgia in patients from North India. Pain Practice 2013; 4: 264-275.
  • Banerjee BD and Jain S. Secondary cigarette smoke causes DNA damage: Susceptibility for disease development. Indian Pediatrics2012; 49 (12): 948-949.
  • Subramaneyaan M*, Jain S*, Yadav C, Arora VK, Banerjee BD, Ahmed RS. Quinalphos induced oxidative stress and histoarcheitectural alterations in adult male albino rats. Environmental Toxicology & Pharmacology 2012; 34(3):673-678.
  • Jain S, Ahmed RS, Arora VK, Banerjee BD. Biochemical and Histopathological studies to assess chronic toxicity of Triazophos in blood, liver and brain tissues of rats. Pesticide Biochemistry & Biophysics 2011; 100: 182–186.
  • Jain S, Mythily S, Yadav CS, Ahmed RS, Arora VK, Tripathi AK, Banerjee BD. Induction of Oxidative stress and Histopathological alterations by Triazophos at Sub- chronic doses. Indian Journal of Biochemistry & Biophysics 2010; 47:388-392.

Certifications

Total Certification – 8

  • Certificate of appreciation as resource person at the two day National seminar on ‘ Molecular Biology and life science at Department of Molecular Biology, Central University of Andhra Pradesh.
  • Life membership of Society of Neurochemistry, India
  • Certificate of being an Organizer in the International Conference on Sustainable Biotechnology for Viksit Bharat, Department of Life Science, SSBT, Sharda University.
  • Active Participation in the Annual National Conference on Advances in Plant Biology (APB2024) organized by Hansraj college, Delhi University
  • Best Performer in the field of ERPs for school level by LMS cell and Dean Academics Affair, Sharda University.

Area of Interest

  • Neurodegeneration and its amelioration by plant derived compounds
  • Exploration of molecular cross talk between various neurotransmitters and BBB transporters
  • Xenobiotic Toxicity in various neurological disorders such as migraine, Parkinsons disorder
  • Phytochemicals benefits of various compounds in Parkinsonism