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Dr. Sanjay Kumar

Assistant Professor, Life Science

sanjay.kumar7@sharda.ac.in

About

I completed my PhD in the field of reproductive biology from All India Institute of Medical Sciences, New Delhi. I established the role of human seminal plasma proteins (HSA-PIP complex and carboxypeptidase E) in the reproductive functions. After my PhD, I continued as a post-doctoral fellow in the same lab for 7 months. Then I worked as a scientist in IVF (In vitro Fertilization) laboratory, Department of Presidents Affairs (DOPA), Al Ain, UAE and I established IVF in animal model such as camel. Then I moved to Mayo Clinic, Rochester, US, where I worked as post-doctoral fellow in division of Hematology/Nephrology. During this period, I developed MALDI-TOF/MS based method for the identification of N-glycosylation in IgG light chain in patients with AL amyloidosis. Also, I explored the role of extracellular vesicles microRNA in the progression of kidney disease. Apart from this, I have 4 months of teaching experience as guest faculty for graduate level courses at Jamia Hamdard, Delhi. During my post-doctoral training, I acquired the necessary experimental skill set and writing abilities for a research grants and I developed expertise in clinical biomarker and assay development and cell signaling with a particular interest in the cancer and kidney disease.

Experience
  • 6.5 years (Post-PhD)
  • 1.5 years (Pre-PhD)
Qualification
  • Ph.D
Award & Recognition

  • Bentham Science Ambassador Award by Bentham Science Publishers, 2019.    
  • Awarded Research Associate from Indian Council of Medical Research, New Delhi, India in 2019.   
  • Awarded Public Budgeting Committee (PBC) Post Doc fellowship from Israel Government in 2014- (Not availed.)  
  • Best Poster Presentation Award (Third Prize) in International Conference on Male Reproductive Health, incorporating XIX Annual Congress of Society of Andrology, India held on 13-14 March, 2014 at Amity University, NOIDA, UP, India. 
  • Qualified national level entrance test and interview for admission to PhD in January 2009 in All India Institute of Medical Sciences (AIIMS), New Delhi, India. (Following UGC Guidelines).  
  • Indian Council of Medical Research-Junior Research Fellowship (ICMR- JRF) Award 2008.
  • Graduate Aptitude Test in Engineering (GATE) Award 2005. 
  • Biotech Consortium India Limited (BCIL) fellowship for Biotech Industrial Training Program (BITP) by Department of Biotechnology (DBT), Government of India, Delhi.
  • M.Sc. Scholarship from Department of Biotechnology (DBT), Government of India

Research

  • Nagoor M, Sharma C, Goyal SN, Kumar S, Ojha S (2020). CB2 receptor-selective agonists as candidates for targeting infection, inflammation and immunity in SARS-CoV-2 infections. Drug Development Research. (Accepted).  
  • Jayachandran M, Yuzhakov SV, Kumar S, Milliner SD, Rule AD, Lieske JC (2020). Specific populations of urinary extracellular vesicles and proteins differentiate type 1 primary hyperoxaluria patients without and with nephrocalcinosis or kidney stones. Orphonet Journal of rare Disease. (Accepted).
  • Gonzalez Guerrico AM, Lieske J, Klee G, Kumar S, Wright AM, Lopez-Baez V, Bobart S, Shevell D, Maldonado M, Troost JP, Hogan MC (2020). Urinary CD80 discriminates among glomerular disease types and reflects disease activity. Kidney International Reports. (In press)
  • Ramakrishnan V, Miller K, Haug J, Kimlinger K, Kumar S, Gonsalves W, Rajkumar VS, Kumar S (2019). HDAC inhibition in combination with MEK or BCL-2 inhibition in multiple myeloma. Haematologica. 104(10):2061-2074.
  • Kourelis T, Murray DL, Dasari S,Kumar S,Barnidge D, Madden B, Arendt B, Milani P, Merlini G, Alvarado MR, Kyle RA, Dispenzieri A (2018).MASS‐FIX may allow identification of patients at risk for light chain amyloidosis before the onset of symptoms. Am J Hematol. 93(11):E368-E370.
  • Kumar S, Murray D, Dasari S, Milani P, Barnidge D, Madden B, Kourelis T, Arendt B, Merlini G, Alvarado M, Dispenzieri A (2019).Assay to rapid screening for immunoglobulin light chain glycosylation: a potential path to earlier AL diagnosis. Leukemia. (1):254-257.
  •  Kumar S*, Tinson A, Mulligan BP, Ojha S (2016). Gelatin Binding Proteins in Reproductive Physiology. Indian J Microbiol. 56(4):383-393 (*Corresponding Author).
  • Tomar AK, Kumar S, Chhillar S, Kumaresan A, Singh S, Yadav S (2016). Human Serum Albumin and Prolactin Inducible Protein complex enhances sperm capacitation in vitro. J Protein and proteomics. 7(2):107-113.
  • Kumar S, Tomar AK, Singh S, Gill K, Dey S, Singh S, Yadav S (2014). Heparin binding carboxypeptidase E protein exhibits antibacterial activity in human semen. Int J Biol. Macromol. 64:319-27.
  • Binita K, Kumar S, Sharma VK, Sharma V, Yadav S (2014). Proteomic Identification of Syzygiumcumini Seed Extracts by MALDI-TOF/MS. Appl. Biochem. Biotechnol. 172(4):2091-105.
  • Kumar S, Sharma VK, Singh S, Hariprasad GR, Mal G, Srinivasan A, Yadav S (2013). Proteomic identification of camel seminal plasma: Purification of β-Nerve Growth Factor. Anim. Reprod Sci. 136(4):289-295.
  • Kumar S, Tomar AK, Singh S, Saraswat M, Singh S, Singh TP, Yadav S (2012). Human serum albumin as a new interacting partner of prolactin inducible protein in human seminal plasma. Int J Biol. Macromol. 50 (2):317-322.
  • Yadav VK, Kumar V, Chhikara N, Kumar S, Manral P, Kashav T, Saini S, Srinivasan A, Singh S, Singh TP, Yadav S (2011).Purification and characterization of a native zinc-binding high molecular weight multiprotein complex from human seminal plasma. J Sep Sci. 34 (9):1076-83.
  • Tomar AK, Saraswat M, Chhikara N, Kumar S, Yadav VK, Sooch BS, Singh TP, Yadav S (2010). Differential proteomics of sperm: insights, challenges and future prospects. Biomark Med. 4 (6):905-10.

Book Chapter

  • Sanjay Kumar*, Brendan P Mulligan, Shreesh Ojha, Alex H Tinson. Microbial Sources of Melatonin and its Clinical Application. Editor VC Kalia, Book title Microbial Applications Vol.2 -Biomedicine, Agriculture and Industry Publisher Springer (November 2016). (*Corresponding Author). (DOI 10.1007/978-3-319-52669-0_2)

Area of Interest

  • Kidney Disease
  • Plasma Cell Disorders
  • Reproductive Physiology