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Dr. Niraj Kumar Jha

Assistant Professor, Biotechnology

niraj.jha@sharda.ac.in

About

Dr. Jha has completed his master's degree in Biotechnology from Vellore Institute of Technology, Vellore, India and PhD from Delhi Technological University (Formerly Delhi College of Engineering), New Delhi, India. He has published more than fifteen scientific articles in peer-reviewed International journals, two chapters in International books and authored two novels. He holds membership of several international societies in Neurochemistry, and has received a number of awards and fellowships in the domain of life science research. He has also delivered several scientific talks at National platforms. He has expertise in the field of Neuro-informatics, Alzheimers disease, Cerebral Infarction/Ischemic Stroke, Drug screening and characterization.

Experience
  • 1 Year
Qualification
  • Ph.D in Biotechnology
Award & Recognition

  1. DBT Junior Research Fellowship (DBT-JRF)
  2. DBT Senior Research Fellowship (DBT-SRF)
  3. Technical Education Quality Improvement Programme (TEQIP) Fellowship
  4. "Commendable Research Award" presented for excellence in research during the year 2017 at Delhi Technological University

Research

2019

  1. Niraj Kumar Jha*, Saurabh Kumar Jha, Rohan Kar,  Parma Nand, Kumari Swati, Vineet Kumar Goswami (2019), Nuclear Factor-Kappa β as a therapeutics target for Alzheimers disease, Journal of Neurochemistry (Wiley-Blackwell) Impact factor: 4.86 (*Corresponding Author)
  2. Niraj Kumar Jha, Rohan Kar, and Rituraj Niranjan (2019), ABC transporters in neurological disorders: an important gateway for botanical compounds mediated neuro-therapeutics, Current Topics in Medicinal Chemistry (Bentham Science) Impact factor: 3.44
  3. Kunal Singh, Niraj Kumar Jha, and Abhimanyu Thakur (2019), Spatiotemporal Chromatin Dynamics- A Tell Tale of Circadian Epigenetic Gene Regulation, Life Sciences (Elsevier) Impact factor: 3.46
  4. Fahad Khan, Pratibha Pandey, Tarun Kumar Upadhyay, Asif Jafri, Niraj Kumar Jha, Rashmi Mishra, Vineeta Singh (2019), Anti-cancerous Effect of Rutin against HPV - C33A Cervical Cancer Cells via G0/G1 Cell Cycle Arrest and Apoptotic Induction, Endocrine, Metabolic & Immune Disorders - Drug Targets (Bentham Science) Impact factor: 2.10
  5. Fahad Khan, Pratibha Pandey, Niraj Kumar Jha, Rashmi Mishra, Shweta Sharma (2019), An in silico study on plant-derived inhibitors against a prognostic Biomarker, Jab1, International Journal of Research in Pharmaceutical Sciences (Pharmascope Publications)
  6. Rohan Kar and Niraj Kumar Jha* (2019), A “NOTCH” deeper into the Epithelial-to-Mesenchymal Transition (EMT) program in Breast cancer, genes (MDPI), (Under revision) (*Corresponding Author) Impact factor: 3.33

2018

  1. Niraj Kumar Jha, Renu Sharma, Dhiraj Kumar, Rashmi K Ambasta and Pravir Kumar, (2018), Hypoxia induced signaling activation in Neurodegenerative Diseases: Targets for new therapeutic strategies,  Journal of Alzheimers Disease (IOS Press) 62(1):15-38, Impact factor: 4.17

2017

  1. Niraj Kumar Jha and Pravir Kumar, (2017), "Molecular docking studies for the comparative analysis of different biomolecules to target Hypoxia inducible factor-1α", International Journal of Applied Pharmaceutics, Vol 9 Issue 4, Impact factor: 0.88
  2. Niraj Kumar Jha and Pravir Kumar, (2017), “Biomolecules mediated targeting of Vascular Endothelial Growth Factor in neuronal dysfunction: An in silico approach”, Asian J Pharm Clin Res, Vol 10, Issue 9,  Impact factor: 0.68
  3. Renu Sharma, Dhiraj Kumar, Niraj Kumar Jha, Rashmi K Ambasta and Pravir Kumar, (2017), Re-expression of Cell cycle markers in aged Neurons and Muscles: Whether cells should divide or die?, Biochim Biophys Acta (Molecular Basis of disease), (Elsevier) 1863(1):324-336, Impact factor: 5.47
  4. Niraj Kumar Jha, Dhiraj Kumar, Rashmi K. Ambasta, Pravir Kumar, (2017), Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration, Biochim Biophys Acta (Molecular Basis of disease), (Elsevier) 1863(5):1132-1146, Impact factor: 5.47
  5. Niraj Kumar Jha, Dhiraj Kumar, Renu Sharma, Abhishek Shrivastava, Rashmi K Ambasta and Pravir Kumar (2017), Stress induced synaptic dysfunction and neurotransmitter release in Alzheimer's disease: Can neurotransmitter and Neuromodulator be a potential therapeutic target?, Journal of Alzheimers Disease, (IOS Press)  57(4):1017-1039, Impact factor: 4.17

2016

  1. Pravir Kumar, Dhiraj Kumar, Niraj Kumar Jha and Rashmi K Ambasta, (2016), Ion channels in neurological disorders, Advances in Protein Chemistry and Structural Biology, (Elsevier) 103:97-136, Impact factor: 3.03
  2. Niraj Kumar Jha, Pravir Kumar and Rashmi K Ambasta, (2016), Molecular Chaperones and Ubiquitin Proteasome System in Tumor Biogenesis: An Overview, Journal of Cell Biology and Cell Metabolism, Jun 15; 3: 010

2015

  1.  Niraj Kumar Jha, Dhiraj Kumar, Noopur Kejariwal, Renu Sharma, Rashmi K Ambasta and Pravir Kumar, (2015), Impact of IDE and Neprilysin in Alzheimer's disease biology: Characterization of putative cognates for therapeutic applications, Journal of Alzheimers Disease, (IOS Press) 48(4):891-917, Impact factor: 4.17
  2. Rashmi K. Ambasta, Dhiraj Kumar, Renu Sharma, Niraj Kumar Jha, and Pravir Kumar, (2015), Comparative study of anti-angiogenic activities of luteolin, lectin and lupeol biomolecules, Journal of Translational Medicine, (BMC) 13:307, Impact factor: 3.78
  3. Pravir Kumar, Niraj Kumar Jha, Karunya Ramani and Rashmi K Ambasta, (2015), Tau phosphorylation, molecular chaperones, Ubiquitin E3 ligase: clinical relevance in Alzheimers disease, Journal of Alzheimers Disease, (IOS Press) 43(2):341-61; Impact factor: 4.17
  4. Niraj Kumar Jha, Rohan Kar, Rashmi K Ambasta, Pravir Kumar (2015), p38 MAPK and PI3K/AKT signaling in Parkinsons disease, International Journal of Molecular and Cellular Medicine, Spring 4(2):67-86,
  5. Niraj Kumar Jha, Satyaprakash, Rohan Kar, Deepak Rathore, Rashmi K Ambasta and Pravir Kumar, (2015), Epigenetics and angiogenesis in cancer, Epigenetic Advancements in Cancer, 12/2015: BOOK CHAPTER; Springer International publishing AG,  

2014

  1.  Niraj Kumar Jha, Rohan Kar, Rashmi K Ambasta and Pravir Kumar, (2014), Role of oxidative stress, ER stress and Ubiquitin Proteasome system in neurodegeneration, MOJ Cell Science and Report, 01(2),  

Area of Interest

  • Neuro-informatics
  • Alzheimers disease
  • Cerebral Infarction/Ischemic Stroke
  • Drug screening and characterization