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Dr. Mohini Singh

Dr. Mohini Singh

Assistant Professor, Life Science

mohini.singh@sharda.ac.in

About

Dr. Mohini is currently working as Assistant Professor at Sharda University, Greater Noida. She has completed her Masters in Genomics from Madurai Kamaraj University in 2013. She completed her PhD in RNA Molecular Biology from the Department of Microbiology and Cell Biology, Indian Institute of Science Bangalore in 2020. Her work mainly focused on purification and characterization of XRN-2 containing protein complex from C. elegans that degrades miRNAs.

Experience
  • N/A
Qualification
  • PhD.
Award & Recognition

  • Qualified the eligibility test for lectureship-CSIR-NET held on 23.12.2012.
  • Awarded Summer Research Fellowship from Indian Academy of Sciences, Bangalore.
  • Awarded Travel Grant from IISc, Bangalore in 2019 for presenting poster in “RNA 2019”, International conference organized by RNA Society in Krakow, Poland, June 2019.

Research

  • Nagar, A., Prajapati, A., Priya, K., Patel, H., Malik, S., Khan, A.A., Bhattacharya, D. and Singh, M., 2024. Structure-based in-silico identification of natural compounds as potential inhibitors of Ran GTPase for breast cancer treatment. Biocatalysis and Agricultural Biotechnology, p.103325.
  • Verma, N., Singh, M., Kumari, S. and Priya, K., 2024. In-silico studies of isolated biological active fractions of Vachellia nilotica leaves extract against MG 63 cell lines and biological applications. Biocatalysis and Agricultural Biotechnology, 60, p.103276.
  • Nagar A, Dubey A, Sharma A, Singh M. Exploring promising natural compounds for breast cancer treatment: in silico molecular docking targeting WDR5-MYC protein interaction. J Biomol Struct Dyn. 2024 Feb 14:1-15. doi: 10.1080/07391102.2024.2317975. Epub ahead of print. PMID: 38356140.
  • Verma N, Singh M, Bhati P, Khanna S, Ashraf MT, Kumari S, Chatterjee N, Deshwal VK, Rustagi S, Priya K. In Vitro and In Silico Studies on 4-Nitroacetophenone Thiosemicarbazone Potential Cytotoxicity Against A549 Cell Lines. Appl Biochem Biotechnol. 2023 Dec 29. doi: 10.1007/s12010-023-04814-1. Epub ahead of print. PMID: 38157154.
  • Kumari S, Singh M, Nupur, Jain S, Verma N, Malik S, Rustagi S, Priya K. A review on therapeutic mechanism of medicinal plants against osteoporosis: effects of phytoconstituents. Mol Biol Rep. 2023 Sep 7. doi: 10.1007/s11033-023-08751-4.
  • Nalawade R and Singh M. Intracellular compartmentalization: A key determinant of MicroRNA functions. MicroRNA. 2023 April; 12(2). DOI: 10.2174/2211536612666230330184006
  • Karmakar K, Kumar S, Roy D, Singh M, Kolte V, Choudhury A, Sharma G. Comparative genomics reveals the diversity of CRISPR–Cas locus in Azotobacter organisms. Letters in Applied Microbiology. 2023 Jan;76(1):ovac004.
  • Singh M, Wani AR, Kundu P, Chatterjee S (2020). A multifaceted microRNA turnover complex from Caenorhabditis elegans. BioRxiv.  https://doi.org/10.1101/2020.12.28.424526

Certifications

  • PG Diploma in Molecular and biochemical techniques from University of Delhi.
  • Participated in Faculty Development Program on “Design Thinking for Creativity and Innovation” organized by Sharda University (3rd-7th January 2022).
  • Participated in Faculty Development Program on “Recent Advances in Health Sciences” organized by School of Allied Health Sciences, Sharda University (19-23rd May 2022).
  • Participated in Faculty Development Program on “Green technologies and approaches for waste valorization” organized by Department of Lifesciences, SBSR, Sharda University (13th -18th June 2022)
  • Completed an online non-credit course on “COVID-19 contact tracing” authorized from Johns Hopkins University and offered through Coursera (6th May 2022)

Area of Interest

  • RNA Molecular Biology
  • Protein-protein/RNA interaction.
  • In-silico/computational studies