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Dr. Gautam Kumar

Dr. Gautam Kumar

Assistant Professor, Pharmacy

gautam.kumar1@sharda.ac.in

About

Dr. Gautam Kumar completed his Ph.D. from Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, Karnataka. He has more than 6 years of research and teaching experience. He qualified GPAT 2014, NIPER-JEE 2014, GPAT 2018. He received National Doctoral Fellowship from All India Council for Technical Education (AICTE), New Delhi to pursue his Ph.D. He has worked as Assistant Professor at School of Pharmacy, Faculty of Health Sciences, Dr. K N Modi University, Newai, Rajasthan. He was Awarded with first prize for e-poster presentation in “International Conference on Biomedical and Clinical research” Organized by Shri Dharmasthala Manjunatheshwara University and Association of Pharmaceutical Research, Dharwad, Karnataka held on 21st and 22nd November 2022.

He has published 12 Scopus/SCI/SCIE-indexed Research articles in reputed international journals. He also has contributed and published 03 Book chapters with reputed international Publishers. He has served as Scientific committee member during National Conference conducted by Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka in 2022. He has been involved (and gave hands on training for HPLC and In Vitro cell culture techniques) in conducting various Faculty Development Programs and Quality improvement Programs conducted by Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka during his PhD tenure.

His current research area includes various aspects of novel and target-specific drug delivery, nanotechnology, gene delivery for cancer management. Currently he is exploring the pharmaceutical potential of nanocarriers co-loaded with siRNAs and chemotherapeutic agent for HER2-positive breast cancer management.

 

Experience
  • 2 years Teaching,
  • 4.5 years research
Qualification
  • Ph.D.
  • M. S. (Pharm.)
  • B. Pharm
Award & Recognition

  • Received first prize for e-poster presentation in “International Conference on Biomedical and Clinical research” Organized by Shri Dharmasthala Manjunatheshwara University and Association of Pharmaceutical Research, Dharwad, Karnataka held on 21st and 22nd November 2022.
  • Qualified GPAT in the year 2014.
  • Qualified NIPER-JEE in the year 2014.
  • Qualified GPAT in the year 2018.
  • Received AICTE sponsored National Doctoral Fellowship (2018-2022).
  • Successfully volunteered and gave Hands on training for HPLC and In Vitro cell culture techniques to participants in various FDPs and QIPs conducted by Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka. 
  • Served as Scientific committee member in National Conference conducted by Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka in 2022.

Research

  • Kumar G, Nandakumar K, Mutalik S, Rao CM. Biologicals to direct nanotherapeutics towards HER2-positive breast cancers. Nanomedicine. 2020 Jul;27:102197. https://doi.org/10.1016/j.nano.2020.102197. (Impact Factor- 6.458)
  • Kumar G, Dutta P, Parihar VK, Chamallamudi MR, Kumar N. Radiotherapy and Its Impact on the Nervous System of Cancer Survivors. CNS Neurol Disord Drug Targets. 2020;19(5):374-385. https://doi.org/10.2174/1871527319666200708125741. (Impact Factor- 2.824)
  • Kumar, G., Mullick, P., Nandakumar, K. et al. Box–Behnken Design-Based Development and Validation of a Reverse-Phase HPLC Analytical Method for the Estimation of Paclitaxel in Cationic Liposomes. Chromatographia 85, 629–642 (2022). https://doi.org/10.1007/s10337-022-04172-w. (Impact Factor- 2.213)
  • Sodum N, Kumar G, Bojja SL, Kumar N, Rao CM. Epigenetics in NAFLD/NASH: Targets and therapy. Pharmacol Res. 2021 May;167:105484. https://doi.org/10.1016/j.phrs.2021.105484. (Impact Factor- 10.33)
  • Sodum N, Kumar G, Rao V, Kumar N, Rao CM. Treatment Approaches for COVID-19: A Critical Review. Mini Rev Med Chem. 2021;21(13):1747-1769. https://doi.org/10.2174/1389557521666210224161950. (Impact Factor- 3.737)
  • Rao V, Kumar G, Vibhavari RJA, Nandakumar K, Thorat N, Chamallamudi MR, Kumar N. Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond O-6-Methylguanine-DNA Methyltransferase. CNS Neurol Disord Drug Targets. 2022 Apr 4. https://doi.org/10.2174/1871527321666220404180944. (Impact Factor- 2.824)
  • Begum, F., Manandhar, S., Kumar, G. et al. Dehydrozingerone promotes healing of diabetic foot ulcers: a molecular insight. J. Cell Commun. Signal. (2022). https://doi.org/10.1007/s12079-022-00703-0. (Impact Factor- 5.908)
  • Kumar N, Kamath S, Kumar G, et al. Prenatal Learning and Memory: Review on the impact of exposure. Current Pediatric Reviews. 2022 Jun. https://doi.org/10.2174/1573396318666220601160537. (Impact Factor- 3.36)
  • Chowdari Gurram P, Satarker S, Kumar G, Begum F, Mehta C, Nayak U, Mudgal J, Arora D, Nampoothiri M. Avanafil mediated dual inhibition of IKKβ and TNFR1 in an experimental paradigm of Alzheimer's disease: in silico and in vivo approach. J Biomol Struct Dyn. 2022 Dec 19:1-19. https://doi.org/10.1080/07391102.2022.2156924. Epub ahead of print. PMID: 36533331. (Impact Factor- 5.23)
  • Sharma R, Suravarjhula L, Banerjee M, Kumar G, Kumar N. Chimeric Antigen Receptor T-cell Therapy in Cancer: A Critical Review. Current Drug Research Reviews. 2023 Feb. DOI: 10.2174/2589977515666230220092125. PMID: 36825696. (Impact Factor- 2.05)
  • Sodum, N., Rao, V., Cheruku, S.P. Kumar G. et al. Amelioration of high-fat diet (HFD) + CCl4 induced NASH/NAFLD in CF-1 mice by activation of SIRT-1 using cinnamoyl sulfonamide hydroxamate derivatives: in-silico molecular modelling and in-vivo prediction. 3 Biotech 12, 147 (2022). https://doi.org/10.1007/s13205-022-03192-5 (Impact Factor- 2.893)
  • Kumar, Gautam and Rao, C Mallikarjuna (2019) "Passive Vaccination: An emerging tool in immunotherapy of breast cancer," Manipal Journal of Pharmaceutical Sciences: Vol. 5 : Iss. 2 , Article 1. Available at: https://impressions.manipal.edu/mjps/vol5/iss2/1
  • Gautam Kumar, Vanishree Rao, Nitesh Kumar, 13 - Development in efficacy assessment in relevant oncology models for breast cancer nanomedicine, Editor(s): Nanasaheb D. Thorat, Joanna Bauer, In Micro and Nano Technologies, Nanomedicines for Breast Cancer Theranostics, Elsevier, 2020, Pages 299-329, ISBN 9780128200162, https://doi.org/10.1016/B978-0-12-820016-2.00013-6
  • Vanishree Rao, Gautam Kumar, Nitesh Kumar, CHAPTER 10- Pharmacokinetics of nanomedicine for breast cancer, Editor(s): Nanasaheb D. Thorat, Joanna Bauer, In External Field and Radiation Stimulated Breast Cancer Nanotheranostics, IOP Science, 2019, Pages 10-1 to 10-21, 978-0-7503-2416-8. https://doi.org/10.1088/2053-2563/ab2907ch10
  • R.J.A. Vibhavari, Gautam Kumar, Vanishree Rao, Sri Pragnya Cheruku, Nitesh Kumar, Chapter 7 - Nano- pharmacokinetics: biodistribution and toxicology, Editor(s): Nanasaheb D. Thorat, Nitesh Kumar, Nano- Pharmacokinetics and Theranostics, Academic Press, 2021, Pages 117-152, ISBN 9780323850506. https://doi.org/10.1016/B978-0-323-85050-6.00013-X

Presentations in conferences

  • Preparation, characterization and In Vitro evaluation of trastuzumab-decorated siRNA and tamoxifen-loaded liposomes in BT-474 cells. Presented in the International Conference on Biomedical and Clinical research” Organized by Shri Dharmasthala Manjunatheshwara University and Association of Pharmaceutical Research, held at Dharwad, Karnataka on 21st and 22nd November 2022.
  • Development and Validation of RP-HPLC Bioanalytical method for the Estimation of Tamoxifen citrate in plasma samples of SD rats. Presented in the National e-conference on Drug Discovery for CNS Disorders, held between 6th to 10th December 2021. Organized by Department of Pharmacology, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka.
  • Development and Validation of RP-HPLC Bioanalytical method for the Estimation of Paclitaxel in plasma samples of SD rats. Presented in the “1st Virtual Global Cancer Conference” conducted by Global Cancer Consortium, held between 2nd to 4th December 2021. Organized by UK Markey Cancer Foundation, United States.

Certifications

  • Attended and Volunteered AICTE Sponsored Faculty Development Programme (August 19-31, 2019) at Manipal College of Pharmaceutical Sciences, Manipal, Karnataka.
  • Attended AICTE Sponsored Quality Improvement Programme (QIP) (September 17-29, 2018) at Manipal College of Pharmaceutical Sciences, Manipal, Karnataka.
  • Attended NIPER-DRILS INDUSTRY-ORIENTED TRAINING PROGRAMME at NIPER-Hyderabad, from 16th - 20th  December-2019.
  • Have attended and presented papers in 3 National and International Conferences.

Area of Interest

  • Cancer targeting,
  • Targeted drug delivery
  • Gene Therapy, Nanotechnology