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Dr. Saurabh Kumar Jha

Assistant Professor, Biotechnology

saurabh.jha@sharda.ac.in

About

Dr. Saurabh Kumar Jha is working as an Assistant Professor in the School of Engineering and Technology (Department of Biotechnology) at Sharda University, Greater Noida. He obtained his M.Sc.(Biotechnology) degree from VIT University, Vellore, and Ph.D. Degree in Biotechnology (Neurobiology) was awarded from Delhi Technological University (Formerly Delhi College of Engineering). His areas of interest in Stem Cell and expertise include molecular chaperone and ubiquitin E3 ligase in neurodegenerative disorders along with therapeutics action of biomolecules in aged neurons and muscles. He has published 22 papers in peer-reviewed and high impact factor International Journals such as JNC, JAD, BBA, APCS, GENE & JTM (h-Index 08; i10-index 8; Cumulative impact factors 50; Citation Index is 350) and Three books chapters in Springer International publishing AG. He has also got “Commendable Research Excellence Award DTU 2018” from Delhi Technological University, Delhi. Recently, Dr. Jha has received “Best Stem Cell Researcher Award 2019” by Prof. (Dr). Michele Zocchi, University of Turin, Italy. He has also presented more than 17 papers in international symposium and proceedings. Further, He has also designed and introduced the two new courses at level of B.Tech/M.Sc./PGD in “Stem Cell Technology and Regenerative Medicine” & “Genetic Engineering” in Sharda University. Dr. Jha has excellent track record in Teaching, Research and Placement in term of B.Tech and M.Tech Biotechnology at Sharda University. Until now, he has currently guided 03 Ph.D., 02 M.Tech, 02 M.Sc. and more than 10 BS students. He has also served various committee Members of Department of Biotechnology as well as University level. He is the life and regular member of various professional societies across the globe.

 

Experience
  • 7 Years (Research and Teaching)
Qualification
  • M.Sc., Ph.D. Biotechnology(Neurobiology), Delhi Technological University(DCE), Delhi.
  • 2017- Ph.D.-Thesis defense “Signalling Mechanism and Therapeutics action of Biomolecules in Neurodegenerative disorder", Molecular Neuroscience and Functional Genomics Laboratory, Department of Biotechnology, Delhi Technological University (Formerly Delhi College of Engineering), India.
  • 2015-2017- DTU-SRF (MHRD)- Department of Biotechnology, Delhi Technological University (Formerly Delhi College of Engineering), India
  • 2013-2015- DTU-JRF (MHRD)- Department of Biotechnology, Delhi Technological University (Formerly Delhi College of Engineering), India
Award & Recognition

  • Best Stem Cell Researcher Award 2019” by Prof. (Dr). Michele Zocchi, University of Turin, Italy.
  • Commendable Research Excellence Award DTU 2018  , Two Best First Author Papers With High Impact Factor
  • Delhi Technological University (DTU), PhD written Examination and Interview in Biotechnology Engineering. 2013, (DTU-JRF/SRF), Aug-2013-Nov-2017, (Rank-GENERAL -01)
  • Madurai Kamaraj University written test for “Integrated M.Sc- Ph.D” in Genomics, 2012, (Rank-GENERAL-23)
  • BHU M.sc Plant Biotechnology, 2011, (Rank-GENERAL-54)
  • South Asian University (SAU) combined entrance examination 2011 for M.Sc Biotechnology (Rank-GENERAL-63)
  • Pondicherry Central University (PCU) written test for “Biochemistry and Molecular Biology” in Biological Sciences, 2011 (Rank-GENERAL-45)
  • Pondicherry Central University (PCU) written test for “Ecology and Environmental Sciences” in Biological Sciences, 2011 (Rank-GENERAL-22)
  • Executive Board Member-International Association Of StemCell & Regenerative Medicine ( IASRM)
  • Best Stem Cell Researcher Award 2019” by Prof. (Dr). Michele Zocchi, University of Turin, Italy.
  • https://www.sharda.ac.in/connect/news-details/dr-saurabh-kumar-jha-has-received--ldquo-best-stem-cell-researcher-award-2019-quot-
  • Commendable Research Excellence Award DTU 2018    , Two Best First Author Papers with High Impact Factor
  • Delhi Technological University (DTU), PhD written Examination and Interview in Biotechnology Engineering. 2013, (DTU-JRF/SRF), Aug-2013-Nov-2017, (Rank-GENERAL -01)
  • Saurabh Kumar Jha (2019), Expert lecture Career Uplift: Stem Cell & Regenerative Medicine; in the area of Biotechnology on 26th November 2019, Sharda University, Noida, India
  • Interview with Educlasses: Biotechnology is the backbone of Indian GDP in 21ST Century_  http://educlasses.co.in/biotechnology-is-the-backbone-of-indian-gdp-in-21st-century-dr-saurabh-kumar-jha.html#.Xv7o0RoWykE.whatsapp

Research

PEER-REVIEWED PUBLICATIONS

Cumulative impact factor of all publications (13) = 50 (approx.); h-index 8; i10-index 8;

Cumulative citation index = 300

  1. Saurabh Kumar Jha (2020), Embryonic signaling as a therapeutic target of Alzheimers disease, Journal of Neurochemistry (Wiley-Blackwell) (Under Revision).
  2. Rohan Kar, Saurabh Kumar Jha and Niraj Kumar Jha (2020), A “NOTCH” deeper into the Epithelial-to-Mesenchymal Transition (EMT) program in Breast cancer, genes (MDPI),
  3. Niraj Kumar Jha, Saurabh Kumar Jha, Rohan Kar and Vineet Kumar Goswami (2019), Nuclear Factor-Kappa β as a therapeutics target for Alzheimers disease, Journal of Neurochemistry (Wiley-Blackwell)
  4. Niraj Kumar Jha, Saurabh Kumar Jha, Renu Sharma, Dhiraj Kumar, Rashmi K Ambasta and Pravir Kumar (2018), Hypoxia induced signaling activation in Neurodegenerative Diseases: Targets for new therapeutic strategies, , J Alzheimers Dis. 2018;62(1):15-38. doi: 10.3233/JAD-170589.
  5. Saurabh Kumar Jha, Niraj Kumar Jha, Dhiraj Kumar, Rashmi K. Ambasta, Pravir Kumar (2017), Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration, Biochimica et Biophysica Acta, (BBA Molecular Basis of disease; Biochim Biophys Acta. 2017 May;1863(5):1132-1146. doi: 10.1016/j.bbadis.2016.06.015. Epub 2016 Jun 21. Elsevier; ,
  6. Saurabh Kumar Jha, Pravir Kumar*, (2017) "Molecular docking study of neuroprotactiveplant-derived biomolecules in Parkinsons disease". International Journal of Pharmacy and Pharmaceutical Sciences. Vol 9 Issue 9, Sept 2017.
  7. Saurabh Kumar Jha, Pravir Kumar*, (2017) “An insilico study of Naringenin mediated neuroprotection in Parkinson Disease”. Asian J Pharm Clin Res. Vol 10, Issue 8, 2017.
  8. Saurabh Kumar Jha, Niraj Kumar Jha, Dhiraj Kumar, Renu Sharma, Abhishek Shrivastava, Rashmi K Ambasta and Pravir Kumar (2017), Stress induced synaptic dysfunction and neurotransmitter release in Alzheimer's disease: Can neurotransmitter and Neuromodulator be a potential therapeutic target?, Journal of Alzheimers Disease, J Alzheimers Dis. 2017;57(4):1017-1039. doi: 10.3233/JAD-1606232016; ,
  9. Niraj Kumar Jha, Saurabh Kumar Jha, Renu Sharma, Dhiraj Kumar, Rashmi K Ambasta and Pravir Kumar (2018), Hypoxia induced signaling activation in Neurodegenerative Diseases: Targets for new therapeutic strategies, , J Alzheimers Dis. 2018;62(1):15-38. doi: 10.3233/JAD-170589.
  10. Renu Sharma, Dhiraj Kumar, Niraj Kumar Jha, Saurabh Kumar Jha, Rashmi K Ambasta and Pravir Kumar (2016), Re-expression of Cell cycle markers in aged Neurons and Muscles: Whether cells should divide or die?, Biochimica et Biophysica Acta, (BBA Molecular Basis of disease; Elsevier; 1863(1):324-336, ,
  11. Saurabh Kumar Jha, Niraj Kumar Jha, Pravir Kumar and Rashmi K Ambasta (2016), Molecular Chaperones and Ubiquitin Proteasome System in Tumor Biogenesis: An Overview, Journal of Cell Biology and Cell Metabolism, 3: 010
  12. Saurabh Kumar Jha, Niraj Kumar Jha, Rohan Kar, Rashmi K Ambasta, Pravir Kumar (2015), p38 MAPK and PI3K/AKT signaling in Parkinsons disease, International Journal of Molecular and Cellular Medicine (IJMCM), Spring 2015 2015 Spring;4(2):67-86.
  13. Rashmi K. Ambasta, Saurabh Kumar Jha, Dhiraj Kumar, Renu Sharma, Niraj Kumar Jha, and Pravir Kumar (2015) Comparative study of anti-angiogenic activities of luteolin, lectin and lupeol biomolecules, Accepted September 2015, 13:307,  Journal of Translational Medicine,
  14. Niraj Kumar Jha, Saurabh Kumar Jha, Dhiraj Kumar, Noopur Kejariwal, Renu Sharma, Rashmi K Ambasta and Pravir Kumar (2015), Impact of IDE and Neprilysin in Alzheimer's disease biology: Characterization of putative cognates for therapeutic applications. Accepted Journal of Alzheimers Disease 2015; 48(4):891-917. doi: 10.3233/JAD-150379. 14th July 2015,
  15. Pravir Kumar, Dhiraj Kumar, Saurabh Kumar Jha, Niraj Kumar Jha, Rashmi K Ambasta (2015), Ion channels in neurological disorders, Accepted October 2015, Advances in Protein Chemistry and Structural Biology, 2016;103:97-136. doi: 10.1016/bs.apcsb.2015.10.006. Epub 2015 Nov 28.
  16. Pravir Kumar, Niraj Kumar Jha, Saurabh Kumar Jha, Karunya Ramani and Rashmi K Ambasta (2015), Tau phosphorylation, molecular chaperones, Ubiquitin E3 ligase: clinical relevance in Alzheimers disease, Journal of Alzheimers Disease, 2015;43(2):341-61;
  17. Niraj Kumar Jha, Saurabh Kumar Jha, Rohan Kar, Rashmi K Ambasta and Pravir Kumar (2014), Role of oxidative stress, ER stress and Ubiquitin Proteasome system in neurodegeneration, MOJ Cell Science and Report. 07/2014; 01(2).

BOOK CHAPTER

  1. Saurabh Kumar Jha, Rahul Yadav, Kumari Swati, Niraj Kumar Jha, Ankur Sharma, Fahad Khan, Neeraj Kumar, Parma Nand, Prabhjot Kaur, Tanaya Gover, and Geetika Rawat (2020) Alterations in metabolite-derived gene regulation in cancer metabolism. In book: Cancer Cell Metabolism: A Potential Target for Cancer Therapy, Publisher: Springer Nature.
  2. Niraj Kumar Jha, Saurabh Kumar Jha, Ankur Sharma, Rahul Yadav, Pratibha Pandey, Kavindra Kumar Kesari, Neeraj Kumar, Parma Nand, Mansi Agrahari, and Nancy Sanjay Gupta (2020) Clinical relevance of "Biomarkers" in cancer metabolism. In book: Cancer Cell Metabolism: A Potential Target for Cancer Therapy, Publisher: Springer Nature.
  3. Niraj Kumar Jha, Saurabh Kumar Jha, Satyaprakash, Rohan Kar, Deepak Rathore, Rashmi K Ambasta and Pravir Kumar (2015) Epigenetics and angiogenesis in cancer, Epigenetic Advancements in Cancer, Edited by Manoj Mishra, Kumar Bishnupuri, 12/2015: BOOK CHAPTER; Springer International publishing AG.

CONFERENCE, PROCEEDINGS AND SYMPOSIUM

  1. Saurabh Kumar Jha (2019), Invited Speaker, “Research methodology and Clinical Trials and their application in Stem Cell and Regenerative Medicine”, 5th International Regenerative Medicine Conclave, 2019, StemGenn Therapeutics International Conference held during 23rd to 24th November, Holiday Inn Aerocity, Delhi.
  2. Ankita Singh and Saurabh Kumar Jha, (2019), In slico study of Parkin and their therapeutic approaches in Neurodegenerative disorder, BioTrendz: Technological Advancement & Challenges in the field of Biotechnology, 23-24 April, Noida Institute Of Engineering & Technology, Greater Noida, India.
  3. Shalu Mishra, Neetesh Chauhan and Saurabh Kumar Jha (2019), Amyotrophic Lateral Sclerosis? BioTrendz: Technological Advancement & Challenges in the field of Biotechnology, 23-24 April, Noida Institute of Engineering & Technology, Greater Noida, India.
  4. Saurabh Kumar Jha (2018), FDP_ Recent trends in material science and engineering, TEQIP-III sponsored one week Faculty development Programme (FDP) organized by Department of Applied Physics, Delhi Technological University (DTU) from September 17th – September 21st, 2018
  5. Saurabh Kumar Jha and Pravir Kumar*, (2015), Comparative analysis of biomolecules in Parkinsons disease therapeutics, 29th Annual Conference of Society for Neurochemistry India and Advancement in computation Neurochemistry and Neurobiology (SNCI-ACNN), December 19-21, 2015, NEHU Shillong , INDIA
  6. Alka Raina, Saurabh Kumar Jha, Niraj Kumar Jha, Dhiraj kumar, Rashmi K Ambasta and Pravir Kumar*(2015), Putative transcription factor binding elements of ubiquitin E3 ligase in neurodegenerative disorders, 29th Annual Conference of Society for Neurochemistry India and Advancement in computation Neurochemistry and Neurobiology (SNCI-ACNN), December 19-21, 2015, NEHU Shillong , INDIA
  7. Abhisekh Srivastava, Puspendramani Mishra, Dhiraj kumar, Saurabh Kumar Jha, Niraj Kumar Jha, Rashmi K Ambasta and Pravir Kumar* (2015), Relevance of terpenoids and alkaloids in neuroprotection, 29th Annual Conference of Society for Neurochemistry India and Advancement in computation Neurochemistry and Neurobiology (SNCI-ACNN), December 19-21, 2015, NEHU Shillong , INDIA
  8. Swati Sharan, Niraj Kumar Jha, Saurabh Kumar Jha, Dhiraj kumar, Rashmi K Ambasta and Pravir Kumar*(2015), Post-translational modification mechanism in Parkinsons disease pathology, 29th Annual Conference of Society for Neurochemistry India and Advancement in computation Neurochemistry and Neurobiology (SNCI-ACNN), December 19-21, 2015, NEHU Shillong , INDIA
  9. Minal Singh, Niraj Kumar Jha, Saurabh Kumar Jha, Dhiraj kumar, Rashmi K Ambasta and Pravir Kumar* (2015), In silico characterization of holo AβPP promoter and its transactivation modules 29th Annual Conference of Society for Neurochemistry India and Advancement in computation Neurochemistry and Neurobiology (SNCI-ACNN), December 19-21, 2015, NEHU Shillong , INDIA
  10. Abhishek Srivastava, Puspendra M Mishra, Saurabh Kumar Jha, Niraj Kumar Jha, Rashmi K Ambasta and Pravir Kumar (2015), In silico analysis cannaboids in neurodegeneration, 6th World congress on biotechnology, New Delhi, October 5th-7th, J Biotechnol Biomater 2015, 5:6, INDIA
  11. Saurabh Kumar Jha, Niraj Kumar Jha, SatyaPrakash, M. Sonia Angeline, Rashmi K. Ambasta and Pravir Kumar (2014), In silico study of flavonones in neurodegenerative disorders, International Symposium on Translational Neuroscience and XXXII Annual Conference of the Indian Academy of Neurosciences, 01-03 November, NIMHANS Bangalore, INDIA, INDIA
  12. Niraj Kumar Jha, Saurabh Kumar Jha, Satya Prakash, M. Sonia Angeline, Rashmi K. Ambasta and Pravir Kumar (2014), Physiological stress in neurodegeneration: Interatomic partners based on In silco study, International Symposium on Translational Neuroscience and XXXII Annual Conference of the Indian Academy of Neurosciences, 01-03 November, NIMHANS Bangalore, INDIA
  13. Dhiraj Kumar, Niraj Kumar Jha, Saurabh Kumar Jha, Renu Sharma, Kushi Anand, Rashmi K. Ambasta and Pravir Kumar (2014), Anti cancerous drugs as a neuroprotectant: a therapeutic intervention in neurodegenerative disorders, International Symposium on Translational Neuroscience and XXXII Annual Conference of the Indian Academy of Neurosciences, 01-03 November, NIMHANS Bangalore, INDIA
  14. Saurabh Kumar Jha, Niraj Kumar Jha, Rashmi K. Ambasta and Pravir Kumar (2013), Structurally and functionally analyzed new generation anti-aging neuroprotective drugs, NCRTPSB 2013, JMI 16-18 December, INDIA Journal of Protein and Proteomics, Vol.4, No.2 p62, INDIA
  15. Saurabh Kumar Jha, Niraj Kumar Jha, Deepak Rathore, Rashmi K. Ambasta and Pravir kumar (2013), Traditional FDA approved anti-cancerous drugs versus new anti-cancerous drugs: A computational approach, 09-11 December, Bioworld Conference, IIT Delhi, INDIA
  16. Niraj Kumar Jha, Saurabh Kumar Jha, Rashmi K. Ambasta and Pravir kumar (2013) Computer assisted protein analysis in hypoxia signaling, NCRTPSB 2013, JMI 16-18 December, INDIA Journal of Protein and Proteomics, Vol.4, No.2 p37, INDIA
  17. Niraj Kumar Jha, Lakshmi, Binod Koirala, Saurabh Kumar Jha, Renu Sharma, Rohan Kar, Dhiraj, Jitendra Singh, Rashmi K. Ambasta and Pravir kumar; (2013), Identification and validation of key Ubiquitin E3 ligases in type II diabetes: An in silico work; 09-11 December, Bioworld Conference, IIT Delhi, Delhi, INDIA
  18. P. Asthana, A.Sarkar, S. Angeline, Kushi Anand, N. Jaiswal, S.K. Jha, N.K. Jha, Priya Chaterjee R. K. Ambasta, Pravir Kumar* (2012), “Protective effect of naringenin on hypoxia induced muscles degeneration”. 2012-S-7580-SfN (Poster presentation in the annual meeting of Society of Neuroscience, Oct 17, 2012, New Orleans, Poster, USA.

C. WORKSHOP AND SEMINARS ATTENDED

  1. Saurabh Kumar Jha (2019), Pandit Deen Dayal Upadhyay Manch, in association with Manyavar Kanshiram Govt. Degree College, Ghaziabad organized a one day National Seminar on Plastic Waste Free India on January 29, 2019.
  2. Saurabh Kumar Jha (2018), National Conference on advances in biotechnology: An interdisciplinary approach, Department of Biotechnology, Sharda University, Noida, India
  3. Saurabh Kumar Jha (2018), Expert lecture Career Uplift: Stem Cell & Regenerative Medicine; in the area of Biotechnology on 26th November 2019, Sharda University, Noida, India
  4. Saurabh Kumar Jha (2015), Work shop on advancement in computation Neurochemistry and Neurobiology (SNCI ACNN), December 16-18, 2015, NEHU Shillong, INDIA
  5. Participated in conference on “Brain and Brain Sciences: Hot Spot Area in Translational Research” Society for Neurochemistry, India (SNCI) VIT University chapter meeting 13th April, 2012, INDIA
  6. Participated in the special course on “Plant Transgenic Technology” jointly organized by the institute of plant genetics, Gottfried Wilhelm Leibniz University, Hannover, Germany and Indo-German Centre for Excellence in Biosciences(IGCEB) in SBST, VIT University 29th January, 2012, INDIA
  7. 5th International Conference on Science, Engineering and Technology (SET), VIT UNIVERSITY, 8th November, 2012, INDIA
  8. 4th International Conference on Science, Engineering and Technology (SET), VIT UNIVERSITY,3th May, 2012, INDIA
  9. 3nd International Conference on Science, Engineering and Technology (SET), VIT UNIVERSITY, 17th November, 2011, INDIA

Certifications

  • Participated in the special course on “Plant Transgenic Technology” jointly organized by the institute of plant genetics, Gottfried Wilhelm Leibniz University, Hannover, Germany and Indo-German Centre for Excellence in Biosciences(IGCEB) in SBST, VIT University 29th January, 2012, INDIA
  • Society of Neurochemistry India (SNCI), (India)-Life member
  • Participated in conference on “Brain and Brain Sciences Hot Spot Area in Translational Research” Society for Neurochemistry, India (SNCI) VIT University chapter meeting 13th April, 2012, INDIA

Area of Interest

  • Neuro Biology
  • Molecular Biology
  • Cancer Biology
  • Micro Biology
  • Biochemistry
  • Drug screening and characterization
  • Stem Cell and Regenerative Medicine

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