Dr. Abhimanyu Kumar Jha

About

Dr. Abhimanyu Kumar Jha is a Molecular Biologist and has extensive Research experience in Molecular Biology, Cancer Biology and Animal Biotechnology. Previously he worked as Dean, Faculty of Life Sciences and Head in Department of Biotechnology, Institute of Applied Medicines and Research, Ghaziabad (U.P). He also worked as Head in Department of Biotechnology, IMS Engineering College, Ghaziabad (U.P), India. He did Ph.D. from Department of Biotechnology, Panjab University, Chandigarh, India.

He has published 40 papers in International Journals and 8 papers in National Journal of Repute. He has also published 16 book chapters in books published by Elsevier, Springer and Apple Academic Press etc. He has delivered many keynote lectures, invited talks and chaired the scientific session in several international as well as national conferences.

He is presently working on the epidemiology and epigenetics of Oral Squamous Cell Carcinoma (OSCC) and Cervical Cancer. His research group is also working on Alzheimers disease and Rheumatoid Arthritis as well as the correlation of contaminants present in groundwater with epigenetic changes in cancer. He also worked on the Natural Compounds-Mediated Reversal of promoter methylation of tumor suppressor genes leading to their reactivation in Cervical Cancer and Acute Lymphoid Leukemia Cell Lines.

Experience

• 17 years

Qualification

• M.Sc. from Bundelkhand University, Jhansi
• Ph.D from Panjab University, Chandigarh

Award & Recognition

• Received Certificate of Achievement for proficiency in the application of knowledge and skills pertaining to laws, principles and concept of Thermodynamics by Advanced Educational Institute on 6 June 2021.
• Received Certificate of Appreciation for the contribution in empowering the Nations progress through as an educator by Lingaya's  LLDIMS on 4 June 2021.
• Received the Award for Best Faculty for Research Innovations by GESA in ICES held from 26-28^th December 2020.
• He was awarded the Young Scientist Award by Environment and Social Development Association (ESDA), New Delhi at World Environment Summit January 18-19, 2020.
• Received the Innovative Animal Scientist Award from Prof. Karunakar Singh, Pro-Vice-Chancellor, Harcourt Butler Technical University, Kanpur for his eminent and distinguished work in cancer biology at 1st International Conference on Environment and Society (ICES 2019) held Kanpur on December 22- 23, 2019.
• Got the Young Biotechnologist Award at International Conference on Agriculture, Allied and Applied Sciences held at JNU Convention Centre, Delhi from 28-29th April 2018.
• Got the Young Scientist travel award of US $1200 for presenting his research at ICCB 2008 held at Seoul, South Korea.

Conferences/Workshops/Seminars Organized

• He has successfully organized 5 International Conferences/Seminars, 3 National conferences, 9 FDPs and 8 workshops as Convenor/Coordinator.

Research

Best Oral/Poster Awards

• Got the best oral presentation Award in an invited talk on ‘Ground Water Contamination and its correlation with Epigenetic changes in various kinds of cancer at 1st International Conference on Environment and Society (ICES 2019) held at Harcourt Butler Technical University, Kanpur on December 22- 23, 2019.
• Won the second prize in poster and oral presentation at CHASCON (Chandigarh Science Congress) 2008.
• Won the second prize in poster and oral presentation in AGOICON 2009 held at Ludhiana, India
• Won the best poster award in Biotechnica 2010- Chandigarh.

Fellowships/Exams Cleared

• Cleared CSIR-UGC JRF NET in 2005.

CSIR-JRF from Mar2006- Mar 2008.

CSIR-SRF from Mar 2008-Mar2011.

• Cleared GATE (Life Sciences) in 2004.
• Cleared TOEFL (in 2005) and GRE (in 2006).
• Secured first rank in All India Ph.D. (Biotechnology) entrance of Panjab University, Chandigarh, India in 2005.

Selected Important Research Publications

• Goel,H., Mathur,R., Syeda,S., Gupta, R.K.,  Kumar, A., Shrivastava., A., & Jha, A.K..(2021)Promoter Methylation of LATS1 Gene in Oral Squamous Cell Carcinoma (OSCC) Among North Indian Population ,Asian Pacific Journal of Cancer Prevention;Volume 22(3), Page no.977–982
• Sharan.,M, Ravinuthala, R.P, Mathur, R , Khare.N & Jha, A.K. (2021) In Silico Study Of Effect of Capsaicin Against Hypermethylation Of Tslc-1 To Cure Cervical Cancer, GIS Science Journal, Volume 8, Issue 7, 2021 1159-1176
• Dwivedi, A., Jha, A. K., & Gupta, V. (2020). Impact of MTHFR C677T and A1298C gene polymorphisms on MTX drug toxicity and efficacy profile of RA patients in North India. Meta Gene, 100705.
• Dwivedi.A, Jha, A.K., Gupta.V (2020) Effects of MTHFR genetic polymorphism on inflammatory protein osteopontin in RA patients: A gender-based study in North Indian population Gene Reports ,100737
• Rani, N., Vaishnav, N., Mathur, R., & Jha, A. K. (2020). Apoptotic Activity by Chemo-preventive Natural Compounds against Oral Squamous Cell Carcinoma. Asian Oncology Research Journal, 6-15.
• Goel, H., Singhal, S., Mathur, R., Syeda, S., Gupta, R. K., Kumar, A., & Jha, A. K. (2020). Promoter Hypermethylation of LATS2 Gene in Oral Squamous Cell Carcinoma (OSCC) Among North Indian Population. Asian Pacific Journal of Cancer Prevention, 21(5), 1283-1287.
• Sharma, A., Mathur, R., & Jha, A. K. (2019). Reversal of Hypermethylation in Tumor Suppressor Genes Using Phytochemicals in Cervical Cancer. European Journal of Medicinal Plants, 1-9.
• Chaudhary, A., Saha, D., & Jha, A. K. (2019). The Dichotomic Role of Telomere Shortening- A Review. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 10(3), 478.
•  Nikbakht M, Jha, A.K., Malekzadeh K., Askari.M., Mohammadi.S, Marwaha R.K., Kaul D., Kaur J. (2017). Aberrant promoter hypermethylation of selected apoptotic genes in childhood Acute Lymphoblastic Leukemia among north Indian population. Experimental Oncology, 39(1), 57–64.
• Jha, A.K., Sharma, V., Nikbakht , M., Jain , V., Sehgal , A., Capalash , N.,  Kaur  J. A. (2016). Comparative Analysis of Methylation Status of Tumor Suppressor Genes in Paired Biopsy and Serum Samples from Cervical Cancer Patients among North Indian Population.  Russian Journal of Genetics, 52, 2, 226–230.
• Jha, M., Patel, S.K., Gupta, S., & Jha, A.K. (2016). Shrivastava, A. Promoter Hypermethylation of Tumor Suppressor Genes in Lung Cancer. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7(4), 3166-3174.
• Aggarwal, R., Jha, M., Shrivastava, A., & Jha, A. K. (2015). Natural compounds: role in reversal of epigenetic changes. Biochemistry (Moscow), 80(8), 972-989.
• Sharma, V., Jha, A. K., Kumar, A., Bhatnagar, A., Narayan, G., & Kaur, I. (2015). Curcumin-mediated reversal of p15 gene promoter methylation: implication in anti-neoplastic action against acute lymphoid leukaemia cell line. Folia biologica, 61(2), 81.
• Jha, M., Aggarwal, R., Jha, A. K., & Shrivastava, A. (2015). Natural compounds: DNA methyltransferase inhibitors in oral squamous cell carcinoma. Applied biochemistry and biotechnology, 177(3), 577-594.
• Jha, A. K., Nikbakht, M., Capalash, N., & Kaur, J. (2014). Demethylation of RARβ2 gene promoter by Withania somnifera in HeLa cell line. European Journal of Medicinal Plants, 503-510.
• Jha, A. K., Nikbakht, M., Jain, V., Sehgal, A., Capalash, N., & Kaur, J. (2012). Promoter hypermethylation of p73 and p53 genes in cervical cancer patients among north Indian population. Molecular biology reports, 39(9), 9145-9157.
• Jha, A. K., Nikbakht, M., Jain, V., Capalash, N., & Kaur, J. (2012). p16INK4a and p15INK4b gene promoter methylation in cervical cancer patients. Oncology letters, 3(6), 1331-1335.
• Nikbakht, M., MalekZadeh, K., Jha, A. K., Askari, M., Marwaha, R. K., Kaul, D., & Kaur, J. (2012). Polymorphisms of MTHFR and MTR genes are not related to susceptibility to childhood ALL in North India. Experimental oncology 34 (1), 43-48.
• Jha, A. K., Nikbakht, M., & Kaur, J. (2011). Cervical cancer: Promoter hypermethylation and its reversal. J. Pharm. Res, 4(10), 3378-3382.
• Chandra, R., Dwivedi, V., Shivam, K., & Jha, A. K. (2011). Detection of antimicrobial activity of Oscimum sanctum (Tulsi) & Trigonella foenum graecum (Methi) against some selected bacterial & fungal strains. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 2(4), 809-813.
• Jha, A. K., Kumar, S., Nikbakht, M., Sharma, V., & Kaur, J. (2011). Epigenetics and its role in ageing and cancer. J Med Med Sci, 2(3), 696-713.
• Jha, A. K., M. Nikbakht, G. Parashar, A. Shrivastava, N. Capalash, and J. Kaur. (2010). "Reversal of hypermethylation and reactivation of the RARbeta2 gene by natural compounds in cervical cancer cell lines." Folia Biol (Praha) 56, (5), 195-200.

Some Selected Book Chapters

• Sharan M., Chaudhary & Jha, A. K. (2021). AIDS: Control and possible cure by using Gene Therapy and Gene Editing Technology in the book: “The Holistic and Integrated Approach to Life Style Diseases” Taylor and Francis Group, Apple Academic Press, Page no:1-15
• Mathur R., Shukla S.P., Saini G., & Jha, A. K. (2021) Epigenetic changes caused by the contaminants present in ground water and their reversal using Natural Compounds in the book: “The holistic and Integrated Approach to Life Style Diseases” Taylor and Francis Group, Apple Academic Press Page no:155-169
• Shukla A.S., Jha, A.K., Kumari R., Rawat, K., Syeda, S, Shrivastava A. (2017) Chapter 9, Role of Catechins in Chemosensitization.In the book “Role of Nutraceuticals In Cancer Chemosensitization” (Elsevier) Volume 2, 169-198. 
• Eight Chapters/ contribution(s) have been published in Encyclopedia of Animal Cognition and Behavior by Springer International Publishing AG 2018, edited by Jennifer Vonk and Todd K. Shackelford:

Some of them are:

• Jha, A.K., Jha M., Transcription., https://doi.org/10.1007/978-3- 319-47829-6_2048-1.
• Jha, A.K., Transgenic, https://doi.org/10.1007/978-3-319-47829- 6_2050-1
• Jha, A.K., Trisomy., https://doi.org/10.1007/978-3-319-47829- 6_2051-1
• Mathur, R., Rana, B.S., & Jha, A.K. (2018) Single Nucleotide Polymorphism (SNP), https://doi.org/10.1007/978-3-319-47829-6_2049-1
• Saha D.& Jha, A.K. (2019). Homo erectus., https://doi.org/10.1007/978-3-319-47829-6_1936-1
• Gupta.V, Gupta. A, Shukla.L.I., & Jha, A.K., Prakash, Tripathy B.N. Determination of Michaelis–Menten Enzyme Kinetics Parameters of Alkaline Phosphatase in Clinical Samples, Experimental Protocols in Biotechnology pp 215-236.
• Anand, T., Sharma, R, Singh, R & Jha, A.K., Comparative Study Between First and Second Wave of COVID-19. COVID 19: Impact and Response Volume V (ISBN: 978-93-91768-19-5) pp 31-38

Keynote Lectures/Plenary Talk/ Plenary Session Chair

• Delivered the keynote lecture in the workshop on “Recent Trends in Biological Sciences and different aspects of cancer" at Raja Harpal Singh P. G. College, Jaunpur, Uttar Pradesh on 24 Jan. 2019. He was the Chief Guest at the workshop.
• Delivered the keynote lecture and chaired the plenary session at “2nd World Congress on Biotechnology and Biological Studies (WCBBS)” held at Bangkok, Thailand from October 18-19, 2018.
• Delivered the keynote lecture and chaired the Plenary first day session at “World Congress on Traditional Medicine” held at Bangkok, Thailand from October 22- 23, 2018.    
• Participated in the 4th International Conference on Voice of Healthcare at Pragati Maidan, Delhi as a panelist speaker on the topic 'E-pharmacy: conundrum of legality'. organized in the Medical Fair, Pragati Maidan in February 2019.

Session Chairs and Invited Talk

• Chaired the session at World Environment Summit 2020, organized by Environment and Social Development Association (ESDA), New Delhi from January 18-19, 2020.
• Chaired the session at 1st International Conference on Environment and Society (ICES 2019) held at Harcourt Butler Technical University, Kanpur on December 22- 23, 2019.
• Chaired the technical session & delivered an invited talk in the National Seminar on “Biotechnology Research in India: Current Status & Future Prospects” organized by Department of Biotechnology, School of Chemical & Life Sciences, Jamia Hamdard, New Delhi from March 26– 27, 2019. 
• Chaired the technical session at “2nd National Conference on Advances in Biotechnology: An Interdisciplinary Approach” held at Sharda University from November 2-3, 2018.
• Chaired the technical session in “International Conference on Holistic Medicine” held at Kottayam, Kerala from September 7- 9, 2018. Also delivered an invited talk in this Conference.
• Chaired the technical session in “World Congress on Biotechnology and Biological Studies (WCBBS)” held at New Delhi from November 9-11, 2017. Also worked as a program committee member in this Program.
• Chaired the technical session in the National Conference on “Recent Advancements in Biotechnology and Bioengineering” organized by Sharda University, Greater Noida from November 2-3, 2017.
• Co-chaired a session on “Genomics and Proteomics Based Biomarkers for Diagnosis of Disease” in the UGC SAP (DRS-I), DST (SERB) & ICAR Sponsored National Seminar on “Biotechnology in Health Care: Challenges and Opportunities”, held at Jamia Hamdard (Deemed University) on March 18-19, 2017.
• Delivered an   invited talk on ‘Status of promoter hypermethylation of FHIT Gene in oral squamous cell carcinoma (OSCC) among north Indian population in the UGC SAP (DRS-I), DST (SERB) &ICAR Sponsored National Seminar on ‘Biotechnology in Health Care: Challenges and Opportunities, held at Jamia Hamdard (Deemed University) on March 18-19^, 2017.

Jury Member/Judge

• Appointed as a Jury member from past three years for Tech and Gen in CREO (An International School Competition) held at Nehru World School in which more than 200 schools participated
• Appointed as one of the Judges for the Regional Scientific Exhibition organized by CBSE in 2019.

Important Subjects Taught

• Genetics, Molecular Biology, Enzyme Engineering,
• Fermentation Technology, Analytical Instrumentation
• Animal Biotechnology, Developmental Biology, Biotechnology in Healthcare
• Cancer Biology, Forensic Diagnosis, Biochemistry, Cell Biology

Certification

Memberships of Society

• Life Member, ESDA
• Life Member, GESA
• Life Member, ABRF
• Member, BRSI,
• Member, EACR

Editorial Board

• Invited member of Editorial Board in Open Access Journal of Surgery (OAJS).
• Invited member of Editorial Board in OPR Science Journal.

Number of Students Guided for Research

• Ph.D. Thesis - 1 (Completed), 4 (Ongoing)
• M.Sc. Dissertation – 68
• M.Tech Dissertation – 11
• B. Tech Dissertation – 34

Book Edited

Dr. Abhimanyu Kumar Jha, Mrs. Debajani Nayak, Dr. Deepak Malik, Dr. Vrinda Manjramkar. COVID 19: Impact and Response Volume V (2021), Bhumi Publishing (ISBN: 978-93-91768-19-5)