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Dr. Vimlendu Bhushan Sinha

Assistant Professor, Biotechnology

vb.sinha@sharda.ac.in

About

He was awarded Ph.D in Biotechnology for his work on ‘‘Studies on freezing stress down-regulated genes from Lepidium from Kumaun University, Nainital in 2012. The complete work was carried out at Defence Institute of Bio-energy Research, DRDO, Haldwani. The worked involved isolation and characterization of novel genes involved in cold stress in the identified plant from the Leh, India. The identified ESTs were analysed and selected clones were subjected to RACE which yielded their full length sequences and were further characterized for expression studied using Real time PCR. The isolated genes were functionally validated by their overexpression in Arabidopsis and Nicotiana which elucidated hypersensitvity in the generated transgenics. He joined GGS Indraprastha University as Research Associate and worked on molecular techniques for increasing Nitrogen Use Efficiency (NUE) of rice plants. He was able to develop some morphometric methods for studying rice seeds at germination level under laboratory condition. The identified rice cultivars (showing contrasting differences in germination), were studied in pot experiments for validating yield response and corresponding NUE. He has published 06 publications in high impact international journals and attended 03 national/international conferences during the regime of his research career. He has enhanced his reputation and scientific values by his association with Journal of New science Biotechnology as Editor and Physiology and Molecular Biology of Plants as Assistant Editor.

Experience
  • Around 9.5 years of experience in R & D activities related to plant studies at molecular level.
Qualification
  • PhD (Biotechnology) from Kumaun University, Nainital, Uttarkhand (2012)
  • MSc (Biotechnology) from CCS University, Meerut, Uttar Pradesh (2005)
  • BSc (Zoology Hons) from Vinoba Bhave University, Hazaribag, Jharkhand (2002)
Award & Recognition

  • Awarded JRF and SRF from DRDO at Defence Institute of Bio-energy Research (DIBER) Haldwani, Nainital Uttarakhand during PhD. Received Research Associateship (RA) from ICAR (under NICRA scheme) and CSIR at School of Biotechnology, GGS Indraprastha University, Dwarka, New Delhi.

Research

  • V B Sinha, A Grover, S Singh, V Pande and Z Ahmed (2014) Overexpression of Ran gene from Lepidium latifolium L. (LlaRan) renders transgenic tobacco plants hypersensitive to cold stress hypersensitive to cold stress. Molecular Biology Reports 41 (9), 5989-5996. Imapct factor 2.51
  • V B Sinha, A Grover, M Aslam, V Pande and Z Ahmed (2014) Isolation and characterization of Ras related GTP binding protein from Lepidium latifolium L. reveals its potential role in regulating abiotic stress tolerance.  Acta Physiologia Plantarum 36 (9), 2353-2360 Impact factor 1.51, Citations 02
  • V B Sinha, A Grover, Z Ahmed and V Pande (2014) Isolation and functional characterization of DNA damage repair protein (DRT) from Lepidium latifolium L. Comptes Rendus Biologies 337 (5) 302-310. Impact factor 1.81, Citations 02
  • M Aslam, A Grover, V B Sinha, B Fakher, V Pande, P V Yadav, S M Gupta, S Anandhan and Z Ahmed (2012) Isolation and Characterization of cold responsive NAC gene from Lepidium latifolium. Molecular Biology Reports 399629-9636. Impact factor – 2.51, Citations-13
  • M Aslam, V B Sinha, R K Singh, S Anandhan, V Pande and Z Ahmed (2010) Isolation of cold responsive genes from Lepidium latifolium by suppressive subtraction hybridization. Acta Physiologia Plantarum 32205-210Imapct factor - 1.51, Citations-17
  • N Sharma, V B Sinha, Mohit Jain, Nishtha Lukhmann, Aakaash Harit, S Singh, V Sitaramam, N Raghuram (2013) N-induced germination delay in 21 rice cultivars A potential phenotyping tool for nitrogen use efficiency in Indraprastha International conference on biotechnology held on 22-25 Oct 2013 at GGSIP University, New Delhi.
  • V B Sinha, S Anandhan, V Pande and Z Ahmed (2009) Cloning of Ras related GTP binding proteins from Lepidium latifolium in 5th international congress on Cell and molecular Biology held at Devi Ahilya Bai University Indore held on 2-6 Nov 2009.
  • M Aslam , V B Sinha, R K Singh, S Anandhan and Z Ahmed (2008) Identification of cold responsive genes from Lepidium latifolium. UCOST held at IIT Roorkee from 10-12 Nov 2008.

Certifications

NA

Area of Intrest

  • Plant signal transduction
  • gene expression
  • metabolic engineering
  • abiotic stresses and gene annotation techniques
  • Transgenics