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Dr. Pooja Shukla

Assistant Professor, Allied Health Sciences

pooja.shukla@sharda.ac.in

About

Dr. Pooja Shukla, did her schooling in science background  from Gorakhpur. Graduated from Gorakhpur University, Gorakhpur in 2009 and also did  Post-Graduation in Biotechnology from Gorakhpur University, Gorakhpur in the year 2011. She awarded with her Ph.D. in molecular-onco-pathology in the Department of Pathology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow in 2019. There she has established diagnostic test for lung cancer in the Pathology Department  Thereafter, Dr. Shukla has joined as a Senior Research Fellow in the Department of Surgical-gastroenterology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow.

Now Dr. Shukla has been associated with Sharda Group as Assistant Professor in the Department of Clinical Research in School of Allied Health Sciences , Sharda University.

Experience
  • 9 Years experience in onco-pathology research and teaching
Qualification
  • Ph.D.
Award & Recognition

  • Invited for lecture in IIT Guwahati
  • DST-INSPIRE Fellowship award in 2013
  • UP-CST in 2012

Research

  • Shukla P, Kumari N, Behari A, Krishnani N, Kapoor VK. Mismatch Repair Protein Expression And Molecular Targets in Ampullary Cancer. (communicated in Pancreas Journal)
  • Kumari N, Shukla P, Krishnani N, Behari A, Kapoor VK. Evaluation of Molecular Targets and Mismatch Match Repair Deficiency in Gallbladder Cancer. (Accepted in J Gastrointest Cancer, 2021)
  • Shukla R, Shukla P, Behari A, Khetan D, Chaudhary RK, Tsuchiya Y, Ikoma T, Asai T, Nakamura K, Kapoor VK. Roles of Salmonella typhi and Salmonella paratyphi Gallbladder Cancer Development. Asian Pac J Cancer Prev, 2021;22 (2), 509-16
  • Mishra K, Behari A, Shukla P, Tsuchiya Y, Endoh K, Asai T, komaT,Nakamura K, Kapoor VK. Risk factors for gallbladder cancer development in Northern India: A gallstones-matched, case control study (Accepted in IJMR)
  • Asai T, Tsuchiya Y, Mishra K, Behari A, Shukla P, Ikoma T, Kapoor VK, Nakamura K. Carcinogen Metabolism Pathway and Tumor Suppressor Gene Polymorphisms and Gallbladder Cancer Risk in North Indians: A Hospital-Based Case-Control Study. Asian Pac J Cancer Prev. 2019;20(12):3643-47.
  • Upadhyay A, Anjum B, Godbole NM, Rajak S, Shukla P, Tiwari S, Sinha RA, Godbole MM. Time-restricted feeding reduces high-fat diet associated placental inflammation and limits adverse effects on fetal organ development. BiochemBiophys Res Commun. 2019;514(2):415-21.
  • Kumari N, Priyaa V, Shukla P, Kumar A, Aggarwal R, Krishnani N. Gastrointestinal Stromal Tumor: Genotype Frequency and Prognostic Relevance. ApplImmunohistochem Mol Morphol. 2018;26(3):153-60.
  • Kumari N, Shukla P, Singh RK, Krishnani N. Mismatch repair protein expression in periampullary carcinoma. Tropical Gastroenterology. 2017;37(4):258-64.
  • Agarwal A, Pradhan R, Kumari N, Krishnani N, Shukla P, Gupta SK, Chand G, Mishra A, Agarwal G, Verma AK, Mishra SK. Molecular Characteristics of Large Parathyroid Adenomas. World J Surg. 2016;40(3):607-14.
  • Kumari N, Singh RK, Krishnani N, Shukla P. Matrix metalloproteinase 7 expression in ampullary carcinoma. Indian J Pathol Microbiol. 2015;58(3):274-78.
  • Krishnani N, Kumari N, Singh RK, Shukla P. The Dominant Somatostatin Receptor in Neuroendocrine Tumors of North Indian Population. World J Endoc Surg. 2015;7(3):60-4.

Certifications

  • Pooja Shukla, Niraj Kumari, Kumudesh Mishra, Ruchira Vishwakarma, Anu Behari, Narendra Krishnani, Vinay K Kapoor. Overexpression and Polymorphism of VEGF, PDGF and HER-2/neu and in Gallbladder Cancer. 5th Annual Conference of Molecular Pathological Association of India and International Symposium on Integration of Genetics and Genomics in Laboratory Medicine at PGIMER Chandigarh, March 2016.
  • Dhanjit Haloi, Niraj Kumari, Shalini Singh, Narendra Krishnani, Pooja Shukla, Shravan K Mishra, Satya S Sarangi. Acquisition of resistance mutation during anti-EGFR therapy in lung adenocarcinoma. XXVth UPPATHCON, KGMU, Lucknow, October 2017.
  • Pooja Shukla, Kumudesh Mishra, Ruchira Vishwakarma, Niraj Kumari, Anu Behari, Narendra Krishnani, Vinay K Kapoor. VEGF expression and its correlation with histopathological parameters in GBC of North Indian Population. New Ideas in Cancer – Challenging Dogmas. Mumbai, February 2016.
  • Narendra Krishnani, Niraj Kumari, Pooja Shukla, Rajneesh Kumar Singh. Clinicopathological significance of matrix metalloproteinase7 expression in ampullary cancer. XXXth Congress of the International Academy of Pathology, Thailand, October 2014.
  • Niraj Kumari, Valli Priya, Pooja Shukla, Narendra Krishnani, Ashok Kumar. Frequency of KIT and PDGFR mutations in gastrointestinal stromal tumor in Indian population. XXXth Congress of the International Academy of Pathology, Thailand, October 2014.

Area of Interest

I have a deep interest in understanding the molecular and immuno-onco-pathology of tumors. My background includes more than 8 years of working experience in the area of molecular onco-pathology. I have got an opportunity to work in the Department of Pathology. I have worked on different types of cancer (thyroid and parathyroid carcinoma, colorectal carcinoma, brain tumors, lung carcinoma (NSCLC), GIST).  By seeing those cases, I have developed an understanding of the mechanism behind the carcinogenesis, and have seen some cases appear with poor clinicopathological features ( TILs, necrosis, LN mets, PNI, LVI) with better survival. What is the possible mechanism behind this? And also wanted to know the tumor microenvironment interaction which can lead to poor survival and precision medicine in human cancers.